ARID5A and SOX5

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		ARID5A	SOX5
Description		AT-rich interaction domain 5A	SRY-box transcription factor 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Nuclear Chromatin
	Molecular Function	DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Transcription Corepressor Activity RNA Binding Protein Binding Transcription Factor Binding Estrogen Receptor Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Retinoid X Receptor Binding Thyroid Hormone Receptor Binding Androgen Receptor Binding	Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Innate Immune Response Negative Regulation Of Transcription, DNA-templated Cellular Response To Estrogen Stimulus	Transcription By RNA Polymerase II Positive Regulation Of Chondrocyte Differentiation Cell Fate Commitment Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Asymmetric Neuroblast Division Positive Regulation Of Cartilage Development Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Mesenchymal Stem Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Eosinophil counts ( 27863252) Eosinophil percentage of white cells ( 27863252) Event-related brain oscillations ( 21184583)	AIDS ( 19754311) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Attention deficit hyperactivity disorder ( 29325848) Body mass index ( 25673413) Chronic back pain ( 30261039) Chronotype ( 30696823) Creatinine levels ( 29403010) Depression ( 29700475) Glomerular filtration rate ( 29403010) Heart rate response to exercise ( 29769521) Heart rate response to recovery post exercise ( 29769521) Heel bone mineral density ( 30598549) Height ( 28552196) Inflammatory bowel disease ( 27569725) Juvenile osteochondritis dissecans ( 26422391) LDL peak particle diameter (total fat intake interaction) ( 26112879) Mortality in sepsis ( 27639821) Non-obstructive azoospermia ( 22197933) Normal facial asymmetry (angle of surface orientation score) ( 30631343) Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070) Pelvic organ prolapse (moderate/severe) ( 26545240) PR interval ( 29127183 30046033 20062060) Response to antipsychotic treatment ( 20195266) Response to statin therapy ( 20339536) Resting heart rate ( 29769521 27798624) Schizophrenia ( 29483656) Systemic sclerosis ( 21779181) Systolic blood pressure ( 30224653) T wave morphology restitution during exercise ( 31607149) T wave morphology restitution during exercise (MTAG) ( 31607149) T wave morphology restitution during recovery from exercise ( 31607149) T wave morphology restitution during recovery from exercise (MTAG) ( 31607149)
Interacting Genes		19 interacting genes: AR ATXN1 CKS1B DAB1 DAZAP2 ESR2 GOLGA2 KRT40 KRTAP12-2 KRTAP12-4 MDFI PNMA1 RARA RBPMS RHOXF2 RXRA SH2D2A SOX5 THRA	26 interacting genes: APP ARID5A CBX8 CDC23 CDC25A CDK6 CRX FTH1 KAT5 KIFC3 LMO1 LMO2 MED27 MORN3 PRR20A RPS2 SMAD1 SMAD5 SMAD7 SOX6 SUMO1P1 TENT5B TLE5 TTC1 UQCRFS1 ZNF581
Entrez ID		10865	6660
HPRD ID		12481	18086
Ensembl ID		ENSG00000196843	ENSG00000134532
Uniprot IDs		Q03989	A0A024RB06 F5H0I3 P35711 T2CYZ2 T2CZM2
PDB IDs
Enriched GO Terms of Interacting Partners?
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