DDIT4L and LSM7

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		DDIT4L	LSM7
Description		DNA damage inducible transcript 4 like	LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Nucleoplasm U6 SnRNP U12-type Spliceosomal Complex Cytosol U4/U6 X U5 Tri-snRNP Complex U2-type Prespliceosome U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome Spliceosomal Tri-snRNP Complex Lsm2-8 Complex Lsm1-7-Pat1 Complex Ribonucleoprotein Complex
	Molecular Function	Protein Binding	Protein Binding U6 SnRNA Binding
	Biological Process	Negative Regulation Of Signal Transduction	MRNA Splicing, Via Spliceosome Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Pathways			mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30643258) Nose size ( 27182965)	Parkinson's disease ( 28892059)
Interacting Genes		7 interacting genes: CALCOCO2 LSM7 MORF4L2 PRKAB2 SNRPG TFPT TNS2	24 interacting genes: ARF6 DDIT4L EPHA2 EXOSC6 EXOSC8 LDB1 LSM1 LSM2 LSM3 LSM4 LSM5 LSM6 LSM8 MYH13 NPY1R PFKM RAB29 RASSF5 SART3 SMN1 SNRPD3 SNRPF TACC1 ZSCAN26
Entrez ID		115265	51690
HPRD ID		09663	06287
Ensembl ID		ENSG00000145358	ENSG00000130332
Uniprot IDs		Q96D03	Q9UK45
PDB IDs			3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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