LSM7 and ZSCAN26

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		LSM7	ZSCAN26
Description		LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated	zinc finger and SCAN domain containing 26
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm U6 SnRNP U12-type Spliceosomal Complex Cytosol U4/U6 X U5 Tri-snRNP Complex U2-type Prespliceosome U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome Spliceosomal Tri-snRNP Complex Lsm2-8 Complex Lsm1-7-Pat1 Complex Ribonucleoprotein Complex	Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding U6 SnRNA Binding	Nucleic Acid Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay	Regulation Of Transcription, DNA-templated
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Parkinson's disease ( 28892059)	Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269)
Interacting Genes		24 interacting genes: ARF6 DDIT4L EPHA2 EXOSC6 EXOSC8 LDB1 LSM1 LSM2 LSM3 LSM4 LSM5 LSM6 LSM8 MYH13 NPY1R PFKM RAB29 RASSF5 SART3 SMN1 SNRPD3 SNRPF TACC1 ZSCAN26	14 interacting genes: CCDC136 CCNDBP1 FSD2 KRTAP10-1 KRTAP10-3 KRTAP10-4 KRTAP10-5 KRTAP10-7 KRTAP10-9 KRTAP4-12 LSM7 MTUS2 PDE4DIP TRIM41
Entrez ID		51690	7741
HPRD ID		06287	15746
Ensembl ID		ENSG00000130332	ENSG00000197062
Uniprot IDs		Q9UK45	A0A024RCN4 A0A087X2F1 B3KTR1 B4DMT1 B4DVH3 Q16670
PDB IDs		3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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