TOE1 and SF3B3

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid)

		TOE1	SF3B3
Description		target of EGR1, exonuclease	splicing factor 3b subunit 3
Image
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Cajal Body Nuclear Body Nuclear Speck	Nucleus Nucleoplasm U12-type Spliceosomal Complex Nucleolus U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	3'-5'-exoribonuclease Activity RNA Binding Poly(A)-specific Ribonuclease Activity Protein Binding SnRNA Binding Metal Ion Binding	Nucleic Acid Binding Protein Binding Protein-containing Complex Binding
	Biological Process	SnRNA 3'-end Processing RNA Phosphodiester Bond Hydrolysis, Exonucleolytic	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Splicing Negative Regulation Of Protein Catabolic Process
Pathways			mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs			Quercetin
Diseases
GWAS			Hippocampal volume in Alzheimer's disease dementia ( 29274321)
Interacting Genes		25 interacting genes: ABCF3 AGGF1 AP2A1 APLP1 CA12 HNRNPF IK IL7R LSM4 PPP1CA PRCC RAB40C RBM39 RBM8A RPS3A SF3B2 SF3B3 SH3GL3 SQSTM1 SRSF6 SUMO1 U2AF1 UNC13B WDR77 WDR83	29 interacting genes: APBB1 EFTUD2 EPS8 ERG HCK HGS HSPB1 KLF10 MPP3 NAGK NOL12 NUTF2 OSGEP PPIL1 PRPF40A RAD9A RBM6 RUFY2 SF3B1 SMAD5 SNRNP200 SREK1 TAF9 TCERG1 TOE1 WBP4 WWOX YWHAG ZNF579
Entrez ID		114034	23450
HPRD ID		18212	12027
Ensembl ID		ENSG00000132773	ENSG00000189091
Uniprot IDs		Q96GM8	A8K6V3 Q15393
PDB IDs		2FC6	5IFE 5O9Z 5Z56 5Z57 5Z58 5ZYA 6AH0 6EN4 6FF4 6FF7 6QX9
Enriched GO Terms of Interacting Partners?
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