LARP4 and CRX

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		LARP4	CRX
Description		La ribonucleoprotein 4	cone-rod homeobox
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Polysome Cytoplasmic Stress Granule Membrane Cytosolic Small Ribosomal Subunit	Nuclear Chromatin Nucleus
	Molecular Function	RNA Binding Protein Binding Poly(A) Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Nuclear Hormone Receptor Binding Leucine Zipper Domain Binding
	Biological Process	Translation Cytoskeleton Organization Regulation Of Cell Morphogenesis Positive Regulation Of Translation	Regulation Of Transcription, DNA-templated Nervous System Development Visual Perception Animal Organ Morphogenesis Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Response To Stimulus
Pathways
Drugs
Diseases			Leber congenital amaurosis (LCR) Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Pulse pressure ( 30578418)
Interacting Genes		4 interacting genes: APP BHLHE40 CRX LRRK2	54 interacting genes: ABI2 ACBD4 ATG12 ATM ATXN7 BANF1 BANP C1orf109 C9orf72 CA8 CCNC CREBBP CSNK1G2-AS1 DELE1 EIF5A EP300 GCM2 GUCD1 HGS IPO13 KAT2A KLHL32 LARP4 LONRF1 M1AP MDFI MLLT6 NIP7 NPAS2 NR2E3 NRL OSGIN1 PDC PICALM PID1 PPP1R16B PRKAB2 PRKN PSMB10 PSMF1 QRICH1 RAX2 RBFOX1 RBPMS ROR2 SFI1 SMAD3 SMUG1 SOX5 STK16 SZT2 TLE5 UBXN2B ZNF688
Entrez ID		113251	1406
HPRD ID		17289	03748
Ensembl ID		ENSG00000161813	ENSG00000105392
Uniprot IDs		Q6P4E2 Q71RC2 Q8TBL5 Q96J85	O43186
PDB IDs		2CQK 3PKN 6I9B
Enriched GO Terms of Interacting Partners?
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