IL17F and GMCL1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		IL17F	GMCL1
Description		interleukin 17F	germ cell-less 1, spermatogenesis associated
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Nucleus Nuclear Matrix
	Molecular Function	Cytokine Activity Cytokine Receptor Binding Protein Binding Cytokine Binding Protein Homodimerization Activity	Protein Binding Identical Protein Binding
	Biological Process	Inflammatory Response Negative Regulation Of Angiogenesis Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cytokine-mediated Signaling Pathway Cytokine Biosynthetic Process Lymphotoxin A Biosynthetic Process Regulation Of Interleukin-2 Biosynthetic Process Regulation Of Interleukin-6 Biosynthetic Process Regulation Of Interleukin-8 Biosynthetic Process Regulation Of Granulocyte Macrophage Colony-stimulating Factor Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Cartilage Development Interleukin-17-mediated Signaling Pathway Positive Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Interleukin-6 Secretion	Multicellular Organism Development Spermatogenesis Cell Differentiation
Pathways		Interleukin-17 signaling Interleukin-4 and Interleukin-13 signaling
Drugs
Diseases		Chronic Mucocutaneous Candidiasis (CMC); Familial candidiasis (CANDF)
GWAS		Initial alcohol sensitivity ( 30276832) Response to gemcitabine in pancreatic cancer ( 22142827) Survival in pancreatic cancer ( 28470677)	Atrial fibrillation ( 28416818 30061737 29892015) Colorectal or endometrial cancer ( 26621817) Whole brain grey matter density ( 31530798)
Interacting Genes		2 interacting genes: GMCL1 RHOU	63 interacting genes: APLF APOL6 AXIN1 BYSL C5orf60 CCDC25 CFAP410 CHIC2 CIB3 CLK2 CUL3 ELOA EMD FKBP1B FOSL2 FOXR1 FRMD6 GAGE1 GAGE12B GAGE12I GAGE2E GAGE5 GLRX3 GMCL2 GOLGA2 GRAMD1A HYKK IL17F KAT5 KIFC3 KPNA2 MID1 MID2 MINDY1 MORF4L1 MPPE1 MTRR NEBL NTAQ1 NUMA1 PARD6B PARP16 PAX4 PBXIP1 PTPN7 QRICH1 RAD54B SHQ1 SLC15A3 SNX20 STK3 SUMO1 SUMO1P1 SYT17 TMPO TRIM13 TRIM38 TRIM54 TSG101 TSSC4 UBE2I XAGE2 ZNF250
Entrez ID		112744	64395
HPRD ID		16224	13587
Ensembl ID		ENSG00000112116	ENSG00000087338
Uniprot IDs		Q96PD4	Q53SE7 Q96IK5
PDB IDs		1JPY 3JVF 5N92 5NAN 6HGO
Enriched GO Terms of Interacting Partners?
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