FUS and SS18

Number of citations of the paper that reports this interaction (PubMedID 30962207)
2

Data Source:
BioGRID (pull down)

		FUS	SS18
Description		FUS RNA binding protein	SS18 subunit of BAF chromatin remodeling complex
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Polysome Perikaryon Dendritic Spine Head Perinuclear Region Of Cytoplasm	Nucleus Cytoplasmic Microtubule SWI/SNF Complex NpBAF Complex
	Molecular Function	DNA Binding Chromatin Binding Transcription Coregulator Activity Transcription Coactivator Activity RNA Binding MRNA 3'-UTR Binding Protein Binding Estrogen Receptor Binding Myosin V Binding Ionotropic Glutamate Receptor Binding Identical Protein Binding Metal Ion Binding Retinoid X Receptor Binding Thyroid Hormone Receptor Binding	Protein Binding Nuclear Receptor Transcription Coactivator Activity
	Biological Process	MRNA Splicing, Via Spliceosome Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II RNA Splicing Regulation Of RNA Splicing MRNA Stabilization Protein Homooligomerization Cellular Response To Calcium Ion Positive Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Double-strand Break Repair Via Homologous Recombination	Microtubule Cytoskeleton Organization Cell Morphogenesis Intracellular Signal Transduction Response To Drug Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Ephrin Receptor Signaling Pathway Neuronal Stem Cell Population Maintenance
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases		Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease Myxoid liposarcoma	Synovial sarcoma
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756)	Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042) Nickel levels ( 26025379) Obesity-related traits ( 23251661) Periodontitis (Mean PAL) ( 24024966) QT interval (sulfonylurea treatment interaction) ( 27958378) Rhegmatogenous retinal detachment ( 23585552) Systemic juvenile idiopathic arthritis ( 27927641) Toenail selenium levels ( 25343990)
Interacting Genes		45 interacting genes: AKT1 ARID1A ATXN1L CTNNB1 ESRRA EWSR1 GRIN1 GRIN2D IL7R ILF3 KHDRBS3 MAX MDH1 NKD2 NUPR1 POLR2A PRMT1 PSMB7 PTBP1 RBMX RELA RXRA SAFB2 SF1 SFPQ SMARCB1 SMARCC1 SMARCC2 SMARCD1 SPI1 SRRM1 SRSF10 SRSF2 SRSF4 SRSF9 SS18 SUV39H1 TARDBP TDRD3 THRA TNIP1 UBQLN2 WBP4 YBX1 ZMYM2	9 interacting genes: EP300 FUS GRB2 H3-3A MLLT10 NFKBID RBM14 SMARCA2 SMARCA4
Entrez ID		2521	6760
HPRD ID		00660	02559
Ensembl ID		ENSG00000089280	ENSG00000141380
Uniprot IDs		P35637 Q13344 Q6IBQ5	A0A024RC40 B4DLD3 B4DR34 B4E2J6 Q15532 Q4VAX0
PDB IDs		2LA6 2LCW 4FDD 4FQ3 5W3N 5XRR 5XSG 5YVG 5YVH 5YVI 6BWZ 6BXV 6BZP 6G99 6GBM 6KJ1 6KJ2 6KJ3 6KJ4
Enriched GO Terms of Interacting Partners?
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