NUDT3 and NR2C1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		NUDT3	NR2C1
Description		nudix hydrolase 3	nuclear receptor subfamily 2 group C member 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nuclear Chromatin Nucleus Nucleoplasm PML Body
	Molecular Function	Magnesium Ion Binding Endopolyphosphatase Activity Diphosphoinositol-polyphosphate Diphosphatase Activity Bis(5'-adenosyl)-hexaphosphatase Activity Bis(5'-adenosyl)-pentaphosphatase Activity M7G(5')pppN Diphosphatase Activity Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Inositol Diphosphate Pentakisphosphate Diphosphatase Activity	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Steroid Hormone Receptor Activity Protein Binding Zinc Ion Binding Signaling Receptor Activity Protein Homodimerization Activity Histone Deacetylase Binding
	Biological Process	Cell-cell Signaling Diadenosine Polyphosphate Catabolic Process Inositol Phosphate Metabolic Process Diphosphoinositol Polyphosphate Metabolic Process Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Pentaphosphate Catabolic Process Diadenosine Hexaphosphate Catabolic Process Adenosine 5'-(hexahydrogen Pentaphosphate) Catabolic Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Cell Differentiation Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Anatomical Structure Development
Pathways		Synthesis of pyrophosphates in the cytosol	Nuclear Receptor transcription pathway SUMOylation of intracellular receptors
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 20935630) Diastolic blood pressure ( 30224653) Estimated glomerular filtration rate ( 30604766) Height ( 25429064 19893584 31562340) Hip circumference ( 25673412)	Body fat mass ( 28552196) Chromosomal aberration frequency (chromosome type) ( 31586183) Trunk fat mass ( 28552196)
Interacting Genes		36 interacting genes: ALAS1 APEX1 ARL6IP1 ASB13 CCL11 CHCHD3 DBN1 DDR1 DNAJA1 EEF1G FXYD3 HES1 ITFG1 MAF1 MCM5 MEX3B NR2C1 NUDT5 OAT PDCD5 PEX5 PRKD3 RAB17 REEP5 RNF126 RPL17 RPL8 RPLP1 SOX30 TNNT3 TUBA1A TUBGCP4 UBR1 VPS51 WDR74 XPNPEP1	7 interacting genes: AR ESR1 HDAC3 HDAC4 NR2C2 NRIP1 NUDT3
Entrez ID		11165	7181
HPRD ID		14849	03318
Ensembl ID		ENSG00000272325	ENSG00000120798
Uniprot IDs		O95989	H9NIM2 H9NIM3 P13056
PDB IDs		2FVV 2Q9P
Enriched GO Terms of Interacting Partners?
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