NUDT3 and RAB17

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NUDT3	RAB17
Description		nudix hydrolase 3	RAB17, member RAS oncogene family
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Intracellular Cell Endomembrane System Basolateral Plasma Membrane Apical Plasma Membrane Endocytic Vesicle Dendrite Melanosome Neuronal Cell Body Recycling Endosome Recycling Endosome Membrane Extracellular Exosome
	Molecular Function	Magnesium Ion Binding Endopolyphosphatase Activity Diphosphoinositol-polyphosphate Diphosphatase Activity Bis(5'-adenosyl)-hexaphosphatase Activity Bis(5'-adenosyl)-pentaphosphatase Activity M7G(5')pppN Diphosphatase Activity Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Inositol Diphosphate Pentakisphosphate Diphosphatase Activity	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Cell-cell Signaling Diadenosine Polyphosphate Catabolic Process Inositol Phosphate Metabolic Process Diphosphoinositol Polyphosphate Metabolic Process Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Pentaphosphate Catabolic Process Diadenosine Hexaphosphate Catabolic Process Adenosine 5'-(hexahydrogen Pentaphosphate) Catabolic Process	Immunoglobulin Transcytosis In Epithelial Cells Mediated By Polymeric Immunoglobulin Receptor Intracellular Protein Transport Establishment Of Melanosome Localization Melanosome Transport Endocytic Recycling Rab Protein Signal Transduction Transcytosis Filopodium Assembly Regulation Of Dendrite Development Regulation Of Filopodium Assembly Regulation Of Synapse Assembly Cilium Assembly
Pathways		Synthesis of pyrophosphates in the cytosol	RAB geranylgeranylation
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 20935630) Diastolic blood pressure ( 30224653) Estimated glomerular filtration rate ( 30604766) Height ( 25429064 19893584 31562340) Hip circumference ( 25673412)	Obesity-related traits ( 23251661)
Interacting Genes		36 interacting genes: ALAS1 APEX1 ARL6IP1 ASB13 CCL11 CHCHD3 DBN1 DDR1 DNAJA1 EEF1G FXYD3 HES1 ITFG1 MAF1 MCM5 MEX3B NR2C1 NUDT5 OAT PDCD5 PEX5 PRKD3 RAB17 REEP5 RNF126 RPL17 RPL8 RPLP1 SOX30 TNNT3 TUBA1A TUBGCP4 UBR1 VPS51 WDR74 XPNPEP1	9 interacting genes: ACVR1 C11orf49 FAM9B MAGEA1 NUDT3 RAB7A RABAC1 S100A8 SMURF2
Entrez ID		11165	64284
HPRD ID		14849	11468
Ensembl ID		ENSG00000272325	ENSG00000124839
Uniprot IDs		O95989	A0A024R4A4 Q9H0T7
PDB IDs		2FVV 2Q9P
Enriched GO Terms of Interacting Partners?
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