KCTD17 and DMC1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		KCTD17	DMC1
Description		potassium channel tetramerization domain containing 17	DNA meiotic recombinase 1
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GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Cul3-RING Ubiquitin Ligase Complex	Chromosome, Telomeric Region Condensed Nuclear Chromosome Nucleus Chromosome
	Molecular Function	Protein Binding Identical Protein Binding Cullin Family Protein Binding	Recombinase Activity DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity Identical Protein Binding
	Biological Process	Cell Projection Organization Endoplasmic Reticulum Calcium Ion Homeostasis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cilium Assembly Protein Homooligomerization	DNA Recombinase Assembly Ovarian Follicle Development Oocyte Maturation Mitotic Recombination Synapsis Reciprocal Meiotic Recombination Male Meiosis I Spermatogenesis Spermatid Development Female Gamete Generation Response To Ionizing Radiation Strand Invasion Meiotic Cell Cycle Chromosome Organization Involved In Meiotic Cell Cycle
Pathways			Meiotic recombination
Drugs			Imidazole
Diseases
GWAS		Iron status biomarkers (ferritin levels) ( 28334935) Mean corpuscular hemoglobin concentration ( 28453575) Red blood cell traits ( 23222517)	Gamma glutamyl transferase levels ( 29403010) Menopause (age at onset) ( 26414677) Sleep duration ( 30846698)
Interacting Genes		19 interacting genes: AQP1 CRK CUL3 DMC1 LNX1 LRRC18 NIF3L1 NUDT18 PLCG2 PSMA1 RBX1 RIN3 RWDD4 STK16 SUV39H2 TCHP TINF2 TUBGCP4 UBE2D1	14 interacting genes: BRCA2 C1orf112 FIGNL1 GORASP2 KCTD17 MSH4 NIF3L1 PSMA3 RAD51 RAD51AP1 RAD54B RPA1 SDCBP TRIM23
Entrez ID		79734	11144
HPRD ID		07764	04099
Ensembl ID		ENSG00000100379	ENSG00000100206
Uniprot IDs		A0A087WX35 Q8N5Z5	Q14565
PDB IDs		5A6R	1V5W 2ZJB 4HYY 6R3P
Enriched GO Terms of Interacting Partners?
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