CIT and RND3

Number of citations of the paper that reports this interaction (PubMedID 12773565)
116

Data Source:
BioGRID (two hybrid)

		CIT	RND3
Description		citron rho-interacting serine/threonine kinase	Rho family GTPase 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Actin Cytoskeleton Membrane Cleavage Furrow	Golgi Membrane Cytoplasm Focal Adhesion Cell Cortex Cytoplasmic Vesicle Cell Division Site Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding SH3 Domain Binding PDZ Domain Binding Metal Ion Binding Scaffold Protein Binding	GTPase Activity Protein Binding GTP Binding Protein Kinase Binding
	Biological Process	Mitotic Cell Cycle Mitotic Cytokinesis Peptidyl-threonine Phosphorylation Cortical Actin Cytoskeleton Organization Actomyosin Structure Organization Positive Regulation Of Cytokinesis Intracellular Signal Transduction Generation Of Neurons Neuron Apoptotic Process	Cytokinesis Actin Filament Organization Cell Adhesion Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Regulation Of Cell Shape Actin Cytoskeleton Organization Regulation Of Cell Migration Establishment Or Maintenance Of Actin Cytoskeleton Polarity Regulation Of Actin Cytoskeleton Organization Actin Filament Bundle Assembly
Pathways		RHO GTPases activate CIT RHO GTPases activate CIT
Drugs			Guanosine-5'-Triphosphate
Diseases
GWAS		Number of sexual partners ( 30643258) Urgency urinary incontinence ( 25524241)	Endometriosis ( 23472165) Esophageal adenocarcinoma x gastroesophageal reflux disease interaction ( 29551738) Platelet count ( 31217584) Type 2 diabetes ( 22238593) Urinary metabolite levels in chronic kidney disease ( 29545352)
Interacting Genes		16 interacting genes: ABCB9 DERA DISC1 DLG4 ENPP7 GRIN1 GRIN2D HIP1R MLXIPL MTNR1A RAC1 RHOA RHOB RHOC RND3 SELPLG	6 interacting genes: ARHGAP5 CIT PLXNB1 ROCK1 SKP2 UBXN11
Entrez ID		11113	390
HPRD ID		09289	04233
Ensembl ID		ENSG00000122966	ENSG00000115963
Uniprot IDs		O14578	B2R838 P61587
PDB IDs			1M7B 2V55 4BG6
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?