TRIM31 and MAGEA2B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRIM31	MAGEA2B
Description		tripartite motif containing 31	MAGE family member A2B
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol Nuclear Body	Nucleus PML Body
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity	Protein Binding Ubiquitin Protein Ligase Binding Histone Deacetylase Binding Repressing Transcription Factor Binding
	Biological Process	Protein Ubiquitination Negative Regulation Of Viral Transcription Innate Immune Response Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Regulation Of Viral Release From Host Cell	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Protein Sumoylation Cellular Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Signal Transduction By P53 Class Mediator Cellular Senescence Negative Regulation Of Protein Acetylation
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		Anger ( 24489884) Autism spectrum disorder or schizophrenia ( 28540026) Beta-2 microglubulin plasma levels ( 23417110) Blood protein levels ( 28240269) Estimated glomerular filtration rate in diabetes ( 31451708) Isovolumetric relaxation time ( 28394258) Mean corpuscular hemoglobin ( 27863252) Neuroticism ( 29255261) Prostate cancer ( 25217961) Type 1 diabetes and autoimmune thyroid diseases ( 25936594)
Interacting Genes		21 interacting genes: EID3 IKBKG MAGEA1 MAGEA2B MKRN3 MNAT1 NLRP3 NSMCE4A TRAF2 TRIM23 TRIM27 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E2 UBE2K UBE2L3 UBE2W USP7 ZSCAN1	10 interacting genes: ANKRD45 CEP57 CEP57L1 KRT8P12 P4HA3 SEPTIN5 TRIM28 TRIM31 TUBB ZNF655
Entrez ID		11074	266740
HPRD ID		10281	14347
Ensembl ID		ENSG00000204616	ENSG00000183305
Uniprot IDs		Q2L6J1 Q9BZY9	A0A024RC17 P43356
PDB IDs		2YSJ 2YSL
Enriched GO Terms of Interacting Partners?
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