MAGEA2B and CEP57

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		MAGEA2B	CEP57
Description		MAGE family member A2B	centrosomal protein 57
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus PML Body	Nucleus Golgi Apparatus Centrosome Cytosol Microtubule
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Histone Deacetylase Binding Repressing Transcription Factor Binding	Protein Binding Microtubule Binding Fibroblast Growth Factor Binding Protein Homodimerization Activity Gamma-tubulin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Protein Sumoylation Cellular Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Signal Transduction By P53 Class Mediator Cellular Senescence Negative Regulation Of Protein Acetylation	G2/M Transition Of Mitotic Cell Cycle Spermatid Development Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Microtubule Anchoring Protein Homooligomerization Ciliary Basal Body-plasma Membrane Docking
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS			Cognitive ability (MTAG) ( 29186694) Erosive tooth wear (severe vs non-severe) ( 29898447) Feeling worry ( 29500382) Intelligence (MTAG) ( 29326435) Rheumatoid arthritis ( 30423114 24390342) Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes		10 interacting genes: ANKRD45 CEP57 CEP57L1 KRT8P12 P4HA3 SEPTIN5 TRIM28 TRIM31 TUBB ZNF655	14 interacting genes: APP FGF2 GCC1 KRT13 KRT15 KRT31 KRT40 MAGEA2B MEGF10 MIA2 MYC RALBP1 TFIP11 UIMC1
Entrez ID		266740	9702
HPRD ID		14347	16261
Ensembl ID		ENSG00000183305	ENSG00000166037
Uniprot IDs		A0A024RC17 P43356	Q86XR8
PDB IDs			4L0R
Enriched GO Terms of Interacting Partners?
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