TOPBP1 and TICRR

Number of citations of the paper that reports this interaction (PubMedID 21700459)
63

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology)

		TOPBP1	TICRR
Description		DNA topoisomerase II binding protein 1	TOPBP1 interacting checkpoint and replication regulator
Image			No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome Spindle Pole Male Germ Cell Nucleus Nucleus Nucleoplasm Chromosome Cytoplasm Microtubule Organizing Center Plasma Membrane Actin Cytoskeleton Nuclear Body PML Body Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm
	Molecular Function	DNA Binding Protein Binding Protein C-terminus Binding Identical Protein Binding	Chromatin Binding Protein Binding
	Biological Process	DNA Metabolic Process DNA Replication DNA Replication Initiation DNA Repair Cellular Response To DNA Damage Stimulus Mitotic G2 DNA Damage Checkpoint Response To Ionizing Radiation Mitotic DNA Replication Checkpoint Regulation Of Signal Transduction By P53 Class Mediator	DNA Replication DNA Repair Mitotic Cell Cycle Checkpoint Response To Ionizing Radiation Regulation Of DNA-dependent DNA Replication Initiation Mitotic DNA Replication Checkpoint
Pathways		HDR through Single Strand Annealing (SSA) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint
Drugs
Diseases
GWAS		Iron status biomarkers ( 19084217)	Resting oxygen saturation in chronic osbtructive pulmonary disease (pulse oxymetry) ( 24825563) Type 2 diabetes ( 31049640)
Interacting Genes		32 interacting genes: ABL1 AKT1 ATM BLM BMPR2 BRIP1 CDC45 CHEK1 CLSTN1 E2F1 ESR1 FHL3 GINS1 HUS1 PML POLE PPHLN1 PPP1CC RAD1 RAD9A RAI1 RBBP8 RHNO1 SF3B2 SMARCAD1 TBC1D4 TCFL5 TEX11 TICRR TOP2B UBR5 ZBTB17	3 interacting genes: APP CRTC3 TOPBP1
Entrez ID		11073	90381
HPRD ID		09678	11357
Ensembl ID		ENSG00000163781	ENSG00000140534
Uniprot IDs		A0AV47 A7E2X7 Q05BV8 Q92547	Q7Z2Z1
PDB IDs		1WF6 2XNH 2XNK 3AL2 3AL3 3JVE 3OLC 3PD7 3UEN 3UEO 6RML 6RMM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?