CPSF6 and WBP4

Number of citations of the paper that reports this interaction (PubMedID 16055720)
81

Data Source:
BioGRID (pull down)

		CPSF6	WBP4
Description		cleavage and polyadenylation specific factor 6	WW domain binding protein 4
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Perichromatin Fibrils Cytoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex MRNA Cleavage Factor Complex Membrane Nuclear Speck Interchromatin Granule Paraspeckles Ribonucleoprotein Complex	Nucleus Nucleoplasm Nuclear Speck U2-type Precatalytic Spliceosome Precatalytic Spliceosome
	Molecular Function	RNA Binding MRNA Binding Protein Binding Ribosomal Large Subunit Binding Exon-exon Junction Complex Binding	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding Proline-rich Region Binding
	Biological Process	MRNA Processing Positive Regulation Of RNA Export From Nucleus Protein Tetramerization Protein Heterotetramerization Pre-mRNA Cleavage Required For Polyadenylation MRNA Alternative Polyadenylation Messenger Ribonucleoprotein Complex Assembly	MRNA Splicing, Via Spliceosome RNA Splicing MRNA Cis Splicing, Via Spliceosome
Pathways		Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Height ( 18391951) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (diuretics) ( 31015401) Pneumoconiosis in silica exposure ( 24986923) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258)	Crohn's disease ( 23266558) CSF tryptophan concentration in tuberculous meningitis ( 29395996) Intraocular pressure ( 29617998) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269)
Interacting Genes		23 interacting genes: APBB1 ARMC7 CSNK2A1 EWSR1 GIN1 ITCH ITSN2 KLHL12 NCK2 NEDD4 NUDT21 OTUB2 PLSCR1 PPIL1 PRPF40A SRSF7 TCERG1 TOLLIP UBAC1 UBQLN4 WBP4 WWP1 WWP2	44 interacting genes: BUB3 CAPRIN1 CHERP CHTF8 CPSF6 CPSF7 DDX23 DDX3X DHX15 DIAPH1 DNM2 EFTUD2 EWSR1 FUS HLTF HNRNPK HNRNPU HTATSF1 KHDRBS1 NONO PABPC1 PRPF3 PRPF4 PRPF40A PSPC1 SART1 SCAF4 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B3 SF3B4 SFPQ SNRNP70 SNRPA SNRPB TCERG1 WAS WBP11 WIPF1 XRCC6 ZNF207
Entrez ID		11052	11193
HPRD ID		05401	16086
Ensembl ID		ENSG00000111605	ENSG00000120688
Uniprot IDs		Q16630	O75554
PDB IDs		3P5T 3P6Y 3Q2S 3Q2T 4B4N 4U0A 4U0B 4WYM 6AY9 6GX9	2DK1 2JXW 5O9Z 6AHD
Enriched GO Terms of Interacting Partners?
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