MAPRE2 and TXN2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MAPRE2	TXN2
Description		microtubule associated protein RP/EB family member 2	thioredoxin 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Organizing Center Microtubule Cytoplasmic Microtubule Focal Adhesion Microtubule Cytoskeleton Microtubule Plus-end Spindle Midzone	Cell Nucleolus Mitochondrion Mitochondrial Matrix Dendrite Neuronal Cell Body
	Molecular Function	Protein Binding Microtubule Binding Protein Kinase Binding Identical Protein Binding Microtubule Plus-end Binding	Protein Binding Peptide-methionine (S)-S-oxide Reductase Activity Protein Disulfide Oxidoreductase Activity Peptide-methionine (R)-S-oxide Reductase Activity Protein-containing Complex Binding
	Biological Process	Regulation Of Microtubule Polymerization Or Depolymerization Positive Regulation Of ARF Protein Signal Transduction Protein Localization To Microtubule Positive Regulation Of GTPase Activity Spindle Assembly Cell Division Positive Regulation Of Keratinocyte Migration Positive Regulation Of Focal Adhesion Disassembly Protein Localization To Microtubule Plus-end	Sulfur Amino Acid Catabolic Process Response To Hypoxia Glycerol Ether Metabolic Process Response To Oxidative Stress Response To Hormone Response To Glucose Response To Organic Cyclic Compound Cellular Response To Nutrient Levels Response To Drug Cell Redox Homeostasis Response To Axon Injury Oxidation-reduction Process
Pathways			Degradation of cysteine and homocysteine Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS		Cerebrospinal fluid AB1-42 levels ( 26252872) Facial morphology ( 29921221) Metabolite levels ( 23823483)
Interacting Genes		24 interacting genes: APC APP AURKA AURKB CASK CDK2 CDK4 CLASP2 CLIP1 FBXO7 GTSE1 LMNA LMO2 MAPRE1 MAPRE3 NIF3L1 PAXIP1 RBM10 RBM6 SLAIN2 TRAF1 TRAIP TXN2 UBC	35 interacting genes: AGTRAP ALDOB AP2B1 CCDC114 DCTD FAM9B GPRASP2 KRT18 KRT40 MAGEA11 MAPRE2 MAPRE3 MLH1 MRFAP1L1 MTUS2 PPCDC PSME3 RABAC1 RABGEF1 RBM45 REEP6 RPIA SCYL3 SHARPIN SSNA1 STUB1 SUN2 THAP1 TIFA TRIM21 TRIP6 UCHL5 VIM VPS52 ZBTB14
Entrez ID		10982	25828
HPRD ID		16157	07161
Ensembl ID		ENSG00000166974	ENSG00000100348
Uniprot IDs		A0A024RC33 Q15555	B4DX69 Q99757
PDB IDs			1UVZ 1W4V 1W89
Enriched GO Terms of Interacting Partners?
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