HNRNPA0 and DDX5

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid, two hybrid)

		HNRNPA0	DDX5
Description		heterogeneous nuclear ribonucleoprotein A0	DEAD-box helicase 5
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Ribonucleoprotein Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Membrane Extracellular Exosome Catalytic Step 2 Spliceosome Ribonucleoprotein Complex
	Molecular Function	RNA Binding MRNA Binding Protein Kinase Binding MRNA 3'-UTR AU-rich Region Binding	RNA Binding RNA Helicase Activity MRNA 3'-UTR Binding Protein Binding Calmodulin Binding ATP Binding Enzyme Binding MH2 Domain Binding Pre-mRNA Binding Ribonucleoprotein Complex Binding SMAD Binding Calcium-dependent Protein Binding Androgen Receptor Binding R-SMAD Binding Primary MiRNA Binding Promoter-specific Chromatin Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing Inflammatory Response RNA Metabolic Process Response To Lipopolysaccharide Regulation Of RNA Metabolic Process 3'-UTR-mediated MRNA Stabilization	Negative Regulation Of Transcription By RNA Polymerase II Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Nuclear-transcribed MRNA Catabolic Process Epithelial To Mesenchymal Transition Regulation Of Transcription By RNA Polymerase II MRNA Transcription BMP Signaling Pathway Intracellular Estrogen Receptor Signaling Pathway Androgen Receptor Signaling Pathway Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Viral Genome Replication Myoblast Differentiation Regulation Of Osteoblast Differentiation Rhythmic Process Regulation Of Androgen Receptor Signaling Pathway Pri-miRNA Transcription By RNA Polymerase II Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Pri-miRNA Transcription By RNA Polymerase II Positive Regulation Of Production Of MiRNAs Involved In Gene Silencing By MiRNA Regulation Of Skeletal Muscle Cell Differentiation
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA	SUMOylation of transcription cofactors mRNA Splicing - Major Pathway Estrogen-dependent gene expression
Drugs
Diseases			Prostate cancer
GWAS			Lung function (FVC) ( 30804560)
Interacting Genes		15 interacting genes: CCT3 CIRBP CLK1 DDX5 HNRNPF HNRNPH2 HNRNPH3 HNRNPK IL7R MAPK6 MAPKAPK2 MTNR1A MTNR1B NKX3-1 SRSF1	35 interacting genes: AKAP8 CALM1 CREBBP DDX17 DHX9 EP300 ESR1 FBL FRS3 HNRNPA0 HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK IL7R KHDRBS1 MAPKAPK2 NCOA1 NCOA2 NCOA3 NDRG1 PIAS1 PIK3CA PIN1 PRKCA PSMA3 RBFOX2 RBM10 RBM4 SMAD3 SP1 TNNT1 TP53 UBE2I WBP11
Entrez ID		10949	1655
HPRD ID		17112	01615
Ensembl ID		ENSG00000177733	ENSG00000108654
Uniprot IDs		Q13151	J3KTA4 P17844
PDB IDs			3FE2 4A4D
Enriched GO Terms of Interacting Partners?
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