DDX5 and HNRNPH1

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (biochemical, two hybrid)

		DDX5	HNRNPH1
Description		DEAD-box helicase 5	heterogeneous nuclear ribonucleoprotein H1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Membrane Extracellular Exosome Catalytic Step 2 Spliceosome Ribonucleoprotein Complex	Nucleus Nucleoplasm Cytosol Membrane Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding RNA Helicase Activity MRNA 3'-UTR Binding Protein Binding Calmodulin Binding ATP Binding Enzyme Binding MH2 Domain Binding Pre-mRNA Binding Ribonucleoprotein Complex Binding SMAD Binding Calcium-dependent Protein Binding Androgen Receptor Binding R-SMAD Binding Primary MiRNA Binding Promoter-specific Chromatin Binding	RNA Binding Protein Binding Poly(U) RNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Nuclear-transcribed MRNA Catabolic Process Epithelial To Mesenchymal Transition Regulation Of Transcription By RNA Polymerase II MRNA Transcription BMP Signaling Pathway Intracellular Estrogen Receptor Signaling Pathway Androgen Receptor Signaling Pathway Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Viral Genome Replication Myoblast Differentiation Regulation Of Osteoblast Differentiation Rhythmic Process Regulation Of Androgen Receptor Signaling Pathway Pri-miRNA Transcription By RNA Polymerase II Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Pri-miRNA Transcription By RNA Polymerase II Positive Regulation Of Production Of MiRNAs Involved In Gene Silencing By MiRNA Regulation Of Skeletal Muscle Cell Differentiation	MRNA Splicing, Via Spliceosome RNA Processing Fibroblast Growth Factor Receptor Signaling Pathway RNA Metabolic Process Regulation Of RNA Splicing
Pathways		SUMOylation of transcription cofactors mRNA Splicing - Major Pathway Estrogen-dependent gene expression	FGFR2 alternative splicing mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs			Copper
Diseases		Prostate cancer
GWAS		Lung function (FVC) ( 30804560)	Daytime sleep phenotypes ( 27126917)
Interacting Genes		35 interacting genes: AKAP8 CALM1 CREBBP DDX17 DHX9 EP300 ESR1 FBL FRS3 HNRNPA0 HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK IL7R KHDRBS1 MAPKAPK2 NCOA1 NCOA2 NCOA3 NDRG1 PIAS1 PIK3CA PIN1 PRKCA PSMA3 RBFOX2 RBM10 RBM4 SMAD3 SP1 TNNT1 TP53 UBE2I WBP11	23 interacting genes: APBB1 CRMP1 DDX5 ERG HIPK3 HNRNPF HNRNPH3 KHSRP MTNR1A NCBP1 NCBP2 NDRG1 PIN1 RALY SF1 SF3B4 SREK1 SUMO2 SUMO4 TCERG1 TOM1L1 YWHAG YWHAQ
Entrez ID		1655	3187
HPRD ID		01615	03021
Ensembl ID		ENSG00000108654	ENSG00000169045
Uniprot IDs		J3KTA4 P17844	A0A384MEJ3 P31943
PDB IDs		3FE2 4A4D	2LXU 6DHS
Enriched GO Terms of Interacting Partners?
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