PRDX3 and FANCC

Number of citations of the paper that reports this interaction (PubMedID 24676280)
3

Data Source:
BioGRID (two hybrid)

		PRDX3	FANCC
Description		peroxiredoxin 3	FA complementation group C
Image			No pdb structure
GO Annotations	Cellular Component	Cell Cytoplasm Mitochondrion Mitochondrial Matrix Early Endosome Cytosol Protein-containing Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Fanconi Anaemia Nuclear Complex
	Molecular Function	Protein Binding Protein C-terminus Binding Thioredoxin Peroxidase Activity Alkyl Hydroperoxide Reductase Activity Kinase Binding Protein Kinase Binding Identical Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process	Protein Binding
	Biological Process	Maternal Placenta Development Apoptotic Process Response To Oxidative Stress Mitochondrion Organization Positive Regulation Of Cell Proliferation Peptidyl-cysteine Oxidation Myeloid Cell Differentiation Response To Lipopolysaccharide Negative Regulation Of Kinase Activity Cellular Response To Oxidative Stress Cellular Response To Reactive Oxygen Species Response To Hydrogen Peroxide Hydrogen Peroxide Catabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cell Redox Homeostasis Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Mitochondrial Membrane Potential Cellular Oxidant Detoxification	Myeloid Cell Homeostasis DNA Repair Nucleotide-excision Repair Germ Cell Development Removal Of Superoxide Radicals Cellular Response To Oxidative Stress Interstrand Cross-link Repair Brain Morphogenesis Protein-containing Complex Assembly Neuronal Stem Cell Population Maintenance
Pathways		Detoxification of Reactive Oxygen Species	Fanconi Anemia Pathway TP53 Regulates Transcription of DNA Repair Genes
Drugs
Diseases			Fanconi anemia
GWAS		Alcoholic chronic pancreatitis ( 28754779)	Birth weight ( 31043758) Offspring birth weight ( 31043758) Polycystic ovary syndrome ( 26284813)
Interacting Genes		12 interacting genes: CUL4B FANCC GORASP2 HNRNPD MAGEA11 MAP3K13 NEK6 NR3C1 PRDX4 RPS6KC1 SUMO4 TNFRSF1A	34 interacting genes: AZIN1 CAPN10 CCNA2 CDK1 CTBP1 DNAJB1 FANCA FANCD2 FANCE FANCF FANCG GSTP1 HSP90AA1 HSP90B1 HSPA1A HSPA4 HSPA8 IK KRT1 MEOX2 MT-ATP6 POR PRDX3 PRPF31 RPL18 RPS3A SPTA1 SPTAN1 STAT1 STMN1 STMN2 TCERG1 USP14 ZBTB32
Entrez ID		10935	2176
HPRD ID		05305	01967
Ensembl ID		ENSG00000165672	ENSG00000158169
Uniprot IDs		A0A384MTR2 P30048	A0A024R9N2 A0A087WW44 B4E3W2 Q00597
PDB IDs		5JCG 5UCX
Enriched GO Terms of Interacting Partners?
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