DBF4 and CDC7

Number of citations of the paper that reports this interaction (PubMedID 10523313)
68

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		DBF4	CDC7
Description		DBF4 zinc finger	cell division cycle 7
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body Dbf4-dependent Protein Kinase Complex	Nucleus Nucleoplasm Cytoplasm Intercellular Bridge Mitotic Spindle
	Molecular Function	Nucleic Acid Binding Protein Binding Enzyme Activator Activity Zinc Ion Binding Protein Serine/threonine Kinase Activator Activity	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Metal Ion Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle DNA Replication Positive Regulation Of Nuclear Cell Cycle DNA Replication Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Cell Cycle Phase Transition	G1/S Transition Of Mitotic Cell Cycle Double-strand Break Repair Via Break-induced Replication DNA Replication Positive Regulation Of Cell Proliferation Positive Regulation Of Nuclear Cell Cycle DNA Replication Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Peptidyl-serine Phosphorylation Cell Cycle Phase Transition Cell Division Negative Regulation Of G0 To G1 Transition
Pathways		Activation of ATR in response to replication stress Activation of the pre-replicative complex	Activation of ATR in response to replication stress Activation of the pre-replicative complex Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Eosinophil percentage of white cells ( 27863252) Gestational age at birth (maternal effect) ( 28877031) Glaucoma (primary open-angle) ( 25861811) Lung function (FEV1/FVC) ( 28166213) Lung function (FVC) ( 26635082) Optic disc area ( 25631615 31798171 28073927 21307088) Optic disc parameters ( 20548946) Optic disc size ( 31809533) Optic nerve measurement (cup-to-disc ratio) ( 28061514) Response to fenofibrate (HDL cholesterol levels) ( 27002377) Vertical cup-disc ratio ( 31798171 25241763 28073927) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		18 interacting genes: BRCA1 CDC7 CDK2 CHAF1A CHEK2 LSM8 MCM2 MCM3 MCM4 MCM6 MCM7 MCMBP MEN1 ORC1 ORC2 ORC3 ORC5 ORC6	26 interacting genes: APP CDK2 CDK4 CDK9 CDKN1A CDKN2A CHAF1A CLSPN CSDE1 DBF4 DBF4B DIAPH1 DTD1 GPT GRHPR MCM10 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 ORC1 ORC5 ORC6 TOB1
Entrez ID		10926	8317
HPRD ID		10371	10345
Ensembl ID		ENSG00000006634	ENSG00000097046
Uniprot IDs		B4DXK0 B7Z8C6 Q9UBU7	A0A384MTU6 B2R6V2 O00311
PDB IDs		4F99 4F9A 4F9B 4F9C	4F99 4F9A 4F9B 4F9C 5UWQ 5UWR
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?