FASTK and WIPF1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FASTK	WIPF1
Description		Fas activated serine/threonine kinase	WAS/WASL interacting protein family member 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Matrix	Ruffle Cytosol Actin Filament Actin Cytoskeleton Actin Cortical Patch Cytoplasmic Vesicle
	Molecular Function	RNA Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Fas-activated Serine/threonine Kinase Activity	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding Actin Filament Binding
	Biological Process	Protein Phosphorylation Regulation Of RNA Splicing Apoptotic Signaling Pathway	Actin Cortical Patch Assembly Endocytosis Actin Polymerization Or Depolymerization Regulation Of Cell Shape Actin Filament-based Movement Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Actin Nucleation Actin Cortical Patch Localization Response To Other Organism Protein-containing Complex Assembly
Pathways			Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Eyebrow thickness ( 26926045)	Atrial fibrillation ( 30061737 29892015) Pulse pressure ( 27841878) Resting heart rate ( 27798624) Systolic blood pressure ( 27841878) Urate levels (BMI interaction) ( 25811787)
Interacting Genes		6 interacting genes: CALCOCO2 MDFI PRPF31 RBPMS TIA1 WIPF1	22 interacting genes: ABI2 ACTC1 ACTG1 ALAS1 APBB1 CDC42 CRKL CTTN FASTK GRB2 HCK HOMER3 ITSN2 NCK1 PRKCQ PRPF40A SEC24C WAS WASL WBP4 WWP2 ZAP70
Entrez ID		10922	7456
HPRD ID		07368	03835
Ensembl ID		ENSG00000164896	ENSG00000115935
Uniprot IDs		A0A090N8I0 A0A090N8Z7 Q14296	A0A140VJZ9 O43516 Q2YDC4
PDB IDs			2A41
Enriched GO Terms of Interacting Partners?
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