GADD45G and PDIA4

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		GADD45G	PDIA4
Description		growth arrest and DNA damage inducible gamma	protein disulfide isomerase family A member 4
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GO Annotations	Cellular Component	Nucleus Cytoplasm	Extracellular Space Cell Endoplasmic Reticulum Endoplasmic Reticulum Lumen Cell Surface Melanosome
	Molecular Function	Protein Binding	RNA Binding Protein Disulfide Isomerase Activity Protein Binding Peptide Disulfide Oxidoreductase Activity
	Biological Process	Activation Of MAPKKK Activity Apoptotic Process Multicellular Organism Development Cell Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of JNK Cascade Regulation Of Cell Cycle Positive Regulation Of Cold-induced Thermogenesis Positive Regulation Of P38MAPK Cascade	Protein Folding Protein Secretion Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis Oxidation-reduction Process Chaperone-mediated Protein Folding
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Automobile speeding propensity ( 30643258) Fibrinogen levels ( 28107422 26561523) General cognitive ability ( 29844566) Hand grip strength ( 29691431) Metabolic syndrome ( 31589552) Nonsyndromic cleft lip with cleft palate ( 28232668) Protein quantitative trait loci ( 18464913) Thyroglobulin plasma levels ( 30929638)	Height ( 20881960)
Interacting Genes		55 interacting genes: AFAP1L1 APP ARPC5L CCNB1 CDK1 CDKN1A CEP57L1 CRIP2 DDAH2 EEF1A1 EEF1G EIF3G ESR1 EZH2 GADD45B GADD45GIP1 GDF9 HAP1 HP IKBKG KAT5 LRIF1 LUC7L LUC7L2 MAP3K4 MED31 MIDN PCNA PDE4DIP PDIA4 PHAX PIAS4 PLEKHM1 PPARA PPARD PPARG PPIL1 PTN PTPRK RAN RARA RBM48 RDH13 REL RWDD2B RXRA SERPINA4 SGK1 SH3GLB1 SH3GLB2 SMARCB1 TRMT2A TSNAX UTP14A ZNF579	3 interacting genes: APOB BCL2L1 GADD45G
Entrez ID		10912	9601
HPRD ID		05383	06501
Ensembl ID		ENSG00000130222	ENSG00000155660
Uniprot IDs		O95257	A0A090N8Y2 P13667
PDB IDs		2WAL 3FFM	3IDV
Enriched GO Terms of Interacting Partners?
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