HSD17B10 and HADHB

Number of citations of the paper that reports this interaction (PubMedID 22496890)
5

Data Source:
BioGRID (two hybrid)

		HSD17B10	HADHB
Description		hydroxysteroid 17-beta dehydrogenase 10	hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix Plasma Membrane Mitochondrial Ribonuclease P Complex	Mitochondrion Mitochondrial Envelope Mitochondrial Outer Membrane Mitochondrial Inner Membrane Endoplasmic Reticulum Mitochondrial Nucleoid
	Molecular Function	TRNA Binding RNA Binding 3-hydroxyacyl-CoA Dehydrogenase Activity Protein Binding Cholate 7-alpha-dehydrogenase Activity Testosterone Dehydrogenase [NAD(P)] Activity Dihydrotestosterone 17-beta-dehydrogenase Activity 3-hydroxy-2-methylbutyryl-CoA Dehydrogenase Activity	RNA Binding 3-hydroxyacyl-CoA Dehydrogenase Activity Acetyl-CoA C-acyltransferase Activity Protein Binding Acetyl-CoA C-myristoyltransferase Activity
	Biological Process	Lipid Metabolic Process Mitochondrion Organization Branched-chain Amino Acid Catabolic Process Protein Homotetramerization Oxidation-reduction Process Mitochondrial TRNA Methylation Mitochondrial TRNA Processing Mitochondrial TRNA 5'-end Processing Mitochondrial TRNA 3'-end Processing	Fatty Acid Beta-oxidation Cardiolipin Acyl-chain Remodeling
Pathways		tRNA processing in the mitochondrion tRNA modification in the mitochondrion Branched-chain amino acid catabolism rRNA processing in the mitochondrion	Acyl chain remodeling of CL Beta oxidation of myristoyl-CoA to lauroyl-CoA mitochondrial fatty acid beta-oxidation of unsaturated fatty acids Beta oxidation of palmitoyl-CoA to myristoyl-CoA Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA Beta oxidation of octanoyl-CoA to hexanoyl-CoA Beta oxidation of hexanoyl-CoA to butanoyl-CoA
Drugs		NADH 1-Azepan-1-Yl-2-Phenyl-2-(4-Thioxo-1,4-Dihydro-Pyrazolo[3,4-D]Pyrimidin-5-Yl)Ethanone Adduct
Diseases		2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency; HSD10 deficiency Non-syndromic X-linked mental retardation Syndromic X-linked mental retardation, including: Turner type (MRXST); Siderius type (MRXSSD) ; Cabezas type (MRXC); Raymond type (MRXSR); Type10 (MRXS10); Type14 (MRXS14); Mental retardation with isolated growth hormone deficiency (MRGH)
GWAS		Bipolar disorder ( 31043756) Body mass index ( 28892062)
Interacting Genes		31 interacting genes: ALDH3B1 ALDOA APP ATP5F1A CHD3 CPS1 CS ETFDH FAF1 GLUD1 GLUL HADHA HADHB HMGCL HMGCS2 HTRA2 MDH1 OGDH PDHA1 PDHB PDHX PINK1 PRKN PYGL TOMM20 TOMM22 TOMM40 TRAF3IP2 TRAF5 TRAF6 UBE2D1	14 interacting genes: ANXA7 APP CDKN1A CHCHD4 COX17 GRB7 HSD17B10 HSPB2 RCC1 SMN1 SUOX TIMM8B TK1 TNNI3K
Entrez ID		3028	3032
HPRD ID		02223	00887
Ensembl ID		ENSG00000072506	ENSG00000138029
Uniprot IDs		A0A0S2Z410 Q99714	F5GZQ3 P55084
PDB IDs		1F67 1SO8 1U7T 2O23	5ZQZ 5ZRV 6DV2
Enriched GO Terms of Interacting Partners?
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