FARS2 and TADA2A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FARS2	TADA2A
Description		phenylalanyl-tRNA synthetase 2, mitochondrial	transcriptional adaptor 2A
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix	PCAF Complex Nucleus Chromosome SAGA-type Complex
	Molecular Function	TRNA Binding Phenylalanine-tRNA Ligase Activity Protein Binding ATP Binding	DNA Binding Chromatin Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Phenylalanyl-tRNA Aminoacylation TRNA Processing	Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Histone Acetylation Histone H3 Acetylation Positive Regulation Of Nucleic Acid-templated Transcription
Pathways		Mitochondrial tRNA aminoacylation	HATs acetylate histones
Drugs		L-Phenylalanine
Diseases
GWAS		Change in glucose in response to thiazide diuretic treatment in hypertension ( 29523524) Copper levels ( 26025379) Height ( 28552196) JT interval (sulfonylurea treatment interaction) ( 27958378) Metabolite levels ( 23823483) Obesity (early onset extreme) ( 23563609) Subjective response to placebo treatment in childhood asthma (change in cough/wheeze) ( 31557306)	Ovarian cancer ( 23535730)
Interacting Genes		23 interacting genes: ADAMTSL4 AGTRAP APPL1 CALCOCO2 CMTM5 HMBOX1 IKZF3 KRT13 KRT31 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-9 MID2 MKRN3 NOTCH2NLA RCBTB2 STX11 TADA2A TFCP2 TRIM27 TRIM54	39 interacting genes: ARNT2 C1orf109 CCDC134 CCHCR1 CDCA7L EIF4E2 EXOC8 FAM107A FANCG FARS2 FBF1 GPSM3 HGS HNRNPLL KAT2A KLC4 KLHL38 KPNA2 MAGOH MCPH1 MFAP1 MTX2 MYC NOL4L-DT NR3C1 PPP1R16B PRKAB2 PRPF31 RNF6 RTL8B SF3A3 TADA3 TCF3 TEKT4 TTC23 TTC9C ZFYVE26 ZNF564 ZNF688
Entrez ID		10667	6871
HPRD ID		09946	03784
Ensembl ID		ENSG00000145982	ENSG00000276234
Uniprot IDs		O95363	A0A024R0Y4 A0A087WWR4 B3KU13 O75478
PDB IDs		3CMQ 3HFV 3TEG 3TUP 5MGH 5MGU 5MGV 5MGW	1X41
Enriched GO Terms of Interacting Partners?
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