FARS2 and MKRN3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FARS2	MKRN3
Description		phenylalanyl-tRNA synthetase 2, mitochondrial	makorin ring finger protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix	Ribonucleoprotein Complex
	Molecular Function	TRNA Binding Phenylalanine-tRNA Ligase Activity Protein Binding ATP Binding	Protein Binding Transferase Activity Identical Protein Binding Metal Ion Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Phenylalanyl-tRNA Aminoacylation TRNA Processing	Protein Ubiquitination
Pathways		Mitochondrial tRNA aminoacylation
Drugs		L-Phenylalanine
Diseases
GWAS		Change in glucose in response to thiazide diuretic treatment in hypertension ( 29523524) Copper levels ( 26025379) Height ( 28552196) JT interval (sulfonylurea treatment interaction) ( 27958378) Metabolite levels ( 23823483) Obesity (early onset extreme) ( 23563609) Subjective response to placebo treatment in childhood asthma (change in cough/wheeze) ( 31557306)	Height ( 31562340) Menarche (age at onset) ( 25231870) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		23 interacting genes: ADAMTSL4 AGTRAP APPL1 CALCOCO2 CMTM5 HMBOX1 IKZF3 KRT13 KRT31 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-9 MID2 MKRN3 NOTCH2NLA RCBTB2 STX11 TADA2A TFCP2 TRIM27 TRIM54	61 interacting genes: ANKRD11 BEX2 CRACR2A ENKD1 ERCC1 FAM110A FAM124B FARS2 GRAP2 KIF1A LRSAM1 MDM2 MDM4 MEOX2 MNAT1 MRPS6 NABP1 NDE1 NKAPD1 PEX10 PEX5 POLR1C PRPF31 PSMA1 RBM41 RBPMS RNF166 RNF32 RNF7 SCNM1 SF1 SFN TCEA2 TCHP TFAP2A TLE5 TRIM23 TRIM31 TRIM34 TRIM5 TRIM65 TRIM8 TSG101 TTC25 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2L3 UBE2N UBE2U UBE2V1 UBE2V2 UBE2W ZNF688
Entrez ID		10667	7681
HPRD ID		09946	04836
Ensembl ID		ENSG00000145982	ENSG00000179455
Uniprot IDs		O95363	Q13064
PDB IDs		3CMQ 3HFV 3TEG 3TUP 5MGH 5MGU 5MGV 5MGW
Enriched GO Terms of Interacting Partners?
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