RAPGEF3 and RAP1A

  • Number of citations of the paper that reports this interaction (PubMedID 10777494)
  • 110
  • Data Source:
  • BioGRID (enzymatic study)

RAPGEF3

RAP1A

Description Rap guanine nucleotide exchange factor 3 RAP1A, member of RAS oncogene family
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bipolar disorder ( 31043756)
  • Body mass index ( 29273807)
  • Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143)
  • Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Crohn's disease ( 30500874)
  • High altitude adaptation ( 28373541)
  • Osteoporosis-related phenotypes ( 20548944)
Interacting Genes 7 interacting genes: AP2B1 DAPK1 MAP1A PNMA1 RAP1A RAP2A RRAS2 43 interacting genes: AFDN APBB1IP ARHGEF1 BIN1 BMX BRAF ELOA FADD FAF1 FAS GABARAPL2 GANAB HDAC1 HSPA1A HSPA4 KRIT1 MTNR1A NTRK1 PDE6D PPP2R1A PRKACA RABAC1 RAF1 RALGDS RAP1GAP RAP1GDS1 RAPGEF1 RAPGEF2 RAPGEF3 RAPGEF4 RAPGEF5 RAPGEF6 RASA1 RASA3 RASGRP2 RASGRP4 RASIP1 RGL4 RGS14 RUNDC3A SMARCA2 SMARCA4 TNFRSF10C
Entrez ID 10411 5906
HPRD ID 06928 01545
Ensembl ID ENSG00000079337 ENSG00000116473
Uniprot IDs O95398 Q99777 A8KAH9 P62834
PDB IDs 1C1Y 1GUA 3KUC 4KVG
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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