RAP1A and RAPGEF4

  • Number of citations of the paper that reports this interaction (PubMedID 10777494)
  • 110
  • Data Source:
  • BioGRID (enzymatic study)

RAP1A

RAPGEF4

Description RAP1A, member of RAS oncogene family Rap guanine nucleotide exchange factor 4
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Crohn's disease ( 30500874)
  • High altitude adaptation ( 28373541)
  • Osteoporosis-related phenotypes ( 20548944)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Fasting plasma glucose ( 25187374)
  • GLP-1 levels in response to oral glucose tolerance test (fasting) ( 29093273)
  • Hippocampal volume ( 25625606)
  • Lateral ventricle temporal horn volume ( 31530798)
Interacting Genes 43 interacting genes: AFDN APBB1IP ARHGEF1 BIN1 BMX BRAF ELOA FADD FAF1 FAS GABARAPL2 GANAB HDAC1 HSPA1A HSPA4 KRIT1 MTNR1A NTRK1 PDE6D PPP2R1A PRKACA RABAC1 RAF1 RALGDS RAP1GAP RAP1GDS1 RAPGEF1 RAPGEF2 RAPGEF3 RAPGEF4 RAPGEF5 RAPGEF6 RASA1 RASA3 RASGRP2 RASGRP4 RASIP1 RGL4 RGS14 RUNDC3A SMARCA2 SMARCA4 TNFRSF10C 12 interacting genes: ATXN1 BMERB1 LRRK2 MAP1A RAP1A RAP2A RIMS2 RRAS2 SWAP70 TRAF2 TSPOAP1 ZC3H11A
Entrez ID 5906 11069
HPRD ID 01545 06929
Ensembl ID ENSG00000116473 ENSG00000091428
Uniprot IDs A8KAH9 P62834 B7Z278 Q8WZA2 X5D7N4
PDB IDs 1C1Y 1GUA 3KUC 4KVG
Enriched GO Terms of Interacting Partners?
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