RAMP3 and KRTAP5-9

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		RAMP3	KRTAP5-9
Description		receptor activity modifying protein 3	keratin associated protein 5-9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Lysosome Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Receptor Complex Amylin Receptor Complex 3 Adrenomedullin Receptor Complex	Cytosol Keratin Filament
	Molecular Function	Amyloid-beta Binding Adrenomedullin Receptor Activity Protein Binding Coreceptor Activity Amylin Receptor Activity	Protein Binding
	Biological Process	Angiogenesis Positive Regulation Of Receptor Recycling Calcium Ion Transport Intracellular Protein Transport G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Gene Expression Positive Regulation Of Protein Kinase A Signaling Positive Regulation Of Cell Death Protein Transport Receptor Internalization Cellular Response To Hormone Stimulus Positive Regulation Of Peptidyl-serine Phosphorylation Cross-receptor Inhibition Within G Protein-coupled Receptor Heterodimer Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Estradiol Stimulus Protein Localization To Plasma Membrane G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Amylin Receptor Signaling Pathway Positive Regulation Of Protein Localization To Plasma Membrane Response To Amyloid-beta Positive Regulation Of Calcium Ion Import Across Plasma Membrane Adrenomedullin Receptor Signaling Pathway	Epidermis Development Keratinization
Pathways		G alpha (s) signalling events Calcitonin-like ligand receptors ADORA2B mediated anti-inflammatory cytokines production	Keratinization
Drugs		Pramlintide
Diseases
GWAS		Hepatic lipid content in extreme obesity ( 25246029)
Interacting Genes		10 interacting genes: CALCR CALCRL HSPB3 KRTAP10-3 KRTAP5-9 NOTCH2NLA NSF PDCD6IP SLC31A2 VIPR1	107 interacting genes: ABHD17A ADAMTSL4 ALPP ATG9A BEX2 BMP7 C10orf62 C11orf87 CATSPER1 CHIC2 CHRD CKS1B CNNM3 COMT CRCT1 CREB5 CTSZ CXCL16 DHRS1 DMRT3 DOCK2 FAH FAM124B FAM161A FAM74A4 FAM76B GLRX3 GNE HOXA1 HOXB9 HPCAL1 HSPD1 JOSD1 KLHL38 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP9-2 KRTAP9-4 LCE1B LCE2A LCE3C LCE3E LCE4A LY6H MAPKBP1 MEOX2 NAXD NCLN NECTIN2 NLK NMU NOTCH2NLA NPBWR2 NPDC1 NTAQ1 NTM NTN4 NUFIP2 OTX1 P2RX4 PCSK5 PFKL PGLS POM121L8P PRKAB2 PSMA1 PTPMT1 RAMP3 RGS20 RNF111 SCARB1 SDC3 SDCBP SHFL SLC22A23 SLC25A10 SMCP SPATC1L SPG7 SPINK2 SPRY2 TBC1D10C TBC1D16 TCEA2 TCEANC TOMM22 TYRO3 YIPF3 ZBTB24 ZFYVE21 ZNF124 ZNF266 ZNF417 ZNF439 ZNF581 ZNF587
Entrez ID		10268	3846
HPRD ID		05517	01008
Ensembl ID		ENSG00000122679	ENSG00000254997
Uniprot IDs		A4D2L1 O60896	P26371
PDB IDs
Enriched GO Terms of Interacting Partners?
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