CTDSPL and SNAI1

Number of citations of the paper that reports this interaction (PubMedID 19004823)
42

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vitro, in vivo)

		CTDSPL	SNAI1
Description		CTD small phosphatase like	snail family transcriptional repressor 1
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GO Annotations	Cellular Component	Nucleus Extracellular Exosome	Nucleus Nucleoplasm Pericentric Heterochromatin Cytoplasm Cytosol
	Molecular Function	Molecular_function Phosphoprotein Phosphatase Activity Protein Binding RNA Polymerase II CTD Heptapeptide Repeat Phosphatase Activity Metal Ion Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Kinase Binding Metal Ion Binding E-box Binding
	Biological Process	Negative Regulation Of Protein Phosphorylation Regulation Of Transcription By RNA Polymerase II Protein Dephosphorylation Biological_process Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Negative Regulation Of Transcription By RNA Polymerase II Osteoblast Differentiation Mesoderm Formation Epithelial To Mesenchymal Transition Aortic Valve Morphogenesis Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Vitamin D Biosynthetic Process Cell Migration Positive Regulation Of Cell Migration Hair Follicle Morphogenesis Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Transcription, DNA-templated Roof Of Mouth Development Cartilage Morphogenesis Trophoblast Giant Cell Differentiation Negative Regulation Of Cell Differentiation Involved In Embryonic Placenta Development Left/right Pattern Formation Notch Signaling Involved In Heart Development Heterochromatin Organization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Bicellular Tight Junction Assembly
Pathways			Regulation of PTEN gene transcription Regulation of PTEN gene transcription
Drugs
Diseases
GWAS		Prostate cancer ( 17903305)	Psoriasis ( 20953189)
Interacting Genes		3 interacting genes: CDK9 FGFR2 SNAI1	33 interacting genes: ACTN2 BRMS1 CTDSP1 CTDSP2 CTDSPL EP300 FBXL14 FBXO22 GSK3B HOXD4 KRT31 KRT40 KRTAP10-3 LATS2 LSP1 MFHAS1 MID2 MTUS2 NBN NOTCH1 NOTCH2NLA OTUB1 PALB2 PAX2 PPIL2 PTEN PTPN1 RCOR1 TGFB1 TNFAIP3 TRIM23 USP17L2 XRCC3
Entrez ID		10217	6615
HPRD ID		12264	05025
Ensembl ID		ENSG00000144677	ENSG00000124216
Uniprot IDs		O15194	O95863
PDB IDs		2HHL	2Y48 3W5K 3ZMT 4QLI
Enriched GO Terms of Interacting Partners?
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