PATJ and NLGN2

Number of citations of the paper that reports this interaction (PubMedID 9647694)
28

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		PATJ	NLGN2
Description		PATJ crumbs cell polarity complex component	neuroligin 2
Image		No pdb structure
GO Annotations	Cellular Component	Centrosome Cytosol Plasma Membrane Bicellular Tight Junction Apical Plasma Membrane Cell Junction Centriolar Satellite Perinuclear Region Of Cytoplasm Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Cell Junction Presynaptic Membrane Cell Projection Synapse Postsynaptic Membrane Inhibitory Synapse Spanning Component Of Membrane Glycinergic Synapse Dopaminergic Synapse Symmetric, GABA-ergic, Inhibitory Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Postsynaptic Specialization Membrane
	Molecular Function	Protein Binding	Signaling Receptor Activity Neurexin Family Protein Binding Identical Protein Binding Cell Adhesion Molecule Binding
	Biological Process	Intracellular Signal Transduction Bicellular Tight Junction Assembly	Regulation Of Respiratory Gaseous Exchange By Neurological System Process Neuron Cell-cell Adhesion Chemical Synaptic Transmission Synapse Assembly Sensory Perception Of Pain Positive Regulation Of Insulin Secretion Positive Regulation Of Synaptic Transmission, GABAergic Protein Localization To Synapse Locomotory Exploration Behavior Cell-cell Junction Maintenance Synaptic Vesicle Endocytosis Modulation Of Chemical Synaptic Transmission Synapse Organization Neuromuscular Process Controlling Balance Positive Regulation Of Synapse Assembly Positive Regulation Of Synaptic Transmission, Glutamatergic Terminal Button Organization Postsynaptic Membrane Assembly Presynaptic Membrane Assembly Gephyrin Clustering Involved In Postsynaptic Density Assembly Postsynaptic Density Protein 95 Clustering Positive Regulation Of Inhibitory Postsynaptic Potential Cell-cell Adhesion Presynapse Assembly Positive Regulation Of Protein Localization To Synapse Inhibitory Synapse Assembly Regulation Of AMPA Receptor Activity Positive Regulation Of Excitatory Postsynaptic Potential Positive Regulation Of Synaptic Vesicle Clustering
Pathways			Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30582445) Excessive daytime sleepiness ( 27992416) Sleep traits (multi-trait analysis) ( 27992416) Type 2 diabetes ( 30297969)	Blood protein levels ( 30072576) Uterine fibroids ( 30194396)
Interacting Genes		28 interacting genes: ADGRB1 ASIC3 CACNG2 CLDN1 CNKSR2 CRB3 CRIPT DDX18 GLS2 GRIN2A GRIN2B GRIN2C GRIN2D KCNA4 KCNJ10 KCNJ15 KCNJ2 KIF1B MAPK12 MPP5 NLGN2 NRXN2 PARD3 PAX6 PRDM16 SCN4A SCN5A TJP3	7 interacting genes: DLG2 DLG3 DLG4 NRXN1 NRXN2 NRXN3 PATJ
Entrez ID		10207	57555
HPRD ID		04434	07348
Ensembl ID		ENSG00000132849	ENSG00000169992
Uniprot IDs			Q8NFZ4
PDB IDs			5XEQ
Enriched GO Terms of Interacting Partners?
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