CDC25A and PEX19

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CDC25A	PEX19
Gene Name		cell division cycle 25A	peroxisomal biogenesis factor 19
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytosol	Nucleus Nucleoplasm Cytoplasm Peroxisome Peroxisomal Membrane Cytosol Integral Component Of Membrane Brush Border Membrane Intracellular Membrane-bounded Organelle Protein Complex
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Protein Kinase Binding	Protein Binding Peroxisome Membrane Class-1 Targeting Sequence Binding Protein N-terminus Binding ATPase Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G1/S Transition Of Mitotic Cell Cycle G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle DNA Replication Mitotic Nuclear Division Cell Proliferation Response To Radiation Cellular Response To UV Peptidyl-tyrosine Dephosphorylation Cell Division Regulation Of Cell Cycle	Protein Targeting To Peroxisome Peroxisome Organization Peroxisome Membrane Biogenesis Peroxisome Fission Protein Import Into Peroxisome Membrane Protein Stabilization Transmembrane Transport Chaperone-mediated Protein Folding Chaperone-mediated Protein Transport Establishment Of Protein Localization To Peroxisome Negative Regulation Of Lipid Binding
Pathways		E2F mediated regulation of DNA replication Ubiquitin Mediated Degradation of Phosphorylated Cdc25A G2/M Checkpoints G2/M Transition G0 and Early G1 Cyclin E associated events during G1/S transition S Phase Cyclin B2 mediated events Cell Cycle, Mitotic Cyclin A/B1 associated events during G2/M transition G1/S Transition Activation of ATR in response to replication stress G1/S-Specific Transcription E2F-enabled inhibition of pre-replication complex formation p53-Independent DNA Damage Response Cell Cycle Checkpoints Cyclin A:Cdk2-associated events at S phase entry p53-Independent G1/S DNA damage checkpoint Mitotic G2-G2/M phases Mitotic G1-G1/S phases Polo-like kinase mediated events G1/S DNA Damage Checkpoints	ABC-family proteins mediated transport ABCA transporters in lipid homeostasis
Drugs
Diseases
GWAS
Protein-Protein Interactions		52 interactors: ANAPC11 APP AR BTRC CAMK1D CCNA1 CCNB1 CCNE1 CCNI CDK1 CDK2 CDKN3 CHEK1 CHEK2 CSNK1A1 CUL3 CUX1 DMD DUSP8 EEF1A1 EGFR FAM193B FBXW11 FGF21 FTH1 FZR1 HLA-C HRAS IL3RA LMO2 MAP3K5 MAPK14 MCM3AP MTAP NAA10 NFKBIB NFYA PEX19 PIM1 POLR1D RAF1 ROCK1 SCYL1 SMAD3 SOX5 UBB VAMP8 XPO1 YWHAB YWHAE YWHAQ YWHAZ	32 interactors: ABCD1 ABCD2 ABCD3 CDC25A CDKN2A EIF1B F11R FKBP7 GSKIP IL23A IRF3 KIFAP3 MFSD5 OIP5 PEX10 PEX11A PEX11B PEX12 PEX13 PEX14 PEX16 PEX26 PEX3 PMP22 PPIB PXMP4 SLC25A17 SLC34A1 SMAD2 SRPK1 STK3 TMEM54
Entrez ID		993	5824
HPRD ID		00305	02610
Ensembl ID		ENSG00000164045	ENSG00000162735
Uniprot IDs		P30304	P40855
PDB IDs		1C25	2W85 2WL8 3AJB 3MK4
Enriched GO Terms of Interacting Partners?		Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Cell Cycle Mitotic Cell Cycle Process Regulation Of Protein Metabolic Process Cell Cycle Process Regulation Of Cell Cycle Cell Cycle Regulation Of Cellular Protein Metabolic Process G2/M Transition Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Phosphorylation G1/S Transition Of Mitotic Cell Cycle Regulation Of Protein Kinase Activity Regulation Of Protein Phosphorylation Regulation Of Kinase Activity Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Protein Metabolic Process Phosphorylation Cellular Response To Organic Substance Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Intracellular Transport Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Apoptotic Process Regulation Of Cellular Component Organization Positive Regulation Of Transferase Activity Positive Regulation Of Gene Expression Apoptotic Signaling Pathway Programmed Cell Death Cellular Response To Growth Factor Stimulus Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cellular Biosynthetic Process Response To Growth Factor Cell Death Death Regulation Of Gene Expression Regulation Of Protein Catabolic Process Phosphate-containing Compound Metabolic Process Protein Phosphorylation Regulation Of Catalytic Activity Response To Stimulus Negative Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription, DNA-templated Regulation Of Ubiquitin-protein Transferase Activity Cellular Protein Modification Process	Peroxisome Organization Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Protein Import Into Peroxisome Matrix Intracellular Protein Transmembrane Transport Protein Transmembrane Transport Peroxisomal Membrane Transport Protein Import Peroxisome Membrane Biogenesis Fatty Acid Oxidation Lipid Oxidation Fatty Acid Catabolic Process Very Long-chain Fatty Acid Catabolic Process Protein Import Into Peroxisome Membrane Organelle Organization Protein To Membrane Docking Transmembrane Transport Establishment Of Protein Localization To Organelle Fatty Acid Beta-oxidation Protein Targeting Cellular Lipid Catabolic Process Protein Localization To Organelle Regulation Of Peroxisome Size Lipid Modification Membrane Biogenesis Carboxylic Acid Catabolic Process Protein Import Into Peroxisome Matrix, Docking Very Long-chain Fatty Acid Metabolic Process Lipid Catabolic Process Cytoplasmic Transport Fatty Acid Alpha-oxidation Fatty Acid Metabolic Process Establishment Of Protein Localization Peroxisome Fission Intracellular Transport Protein Localization Cellular Localization Intracellular Protein Transport Transport Establishment Of Localization In Cell Establishment Of Protein Localization To Membrane Cellular Protein Localization Protein Stabilization Membrane Docking Posttranscriptional Regulation Of Gene Expression Protein Transport Positive Regulation Of Viral Genome Replication Cellular Component Assembly Regulation Of Defense Response To Virus By Host Monocarboxylic Acid Metabolic Process
Tagcloud ?		a2 abstract adenosine analog arrest blocks cdk2 chk2 contributes cordycepin cordyceps cytochrome cytosol erk1 exert inhibits initiates intrinsic involves leads militaris mitochondria nb obscure released sensitizes trigger u937 ways	amphipathic anchored biogenesis chaperone concerted delivers docking engagement hydrophobic hydrophobicity inserted insertion intercalation moieties peroxisome pex3 promotes prompt reconstitute segment segments sequential steps ta tail tmd translationally uncharacterized unconventional
Tagcloud (Difference) ?		a2 abstract adenosine analog arrest blocks cdk2 chk2 contributes cordycepin cordyceps cytochrome cytosol erk1 exert inhibits initiates intrinsic involves leads militaris mitochondria nb obscure released sensitizes trigger u937 ways	amphipathic anchored biogenesis chaperone concerted delivers docking engagement hydrophobic hydrophobicity inserted insertion intercalation moieties peroxisome pex3 promotes prompt reconstitute segment segments sequential steps ta tail tmd translationally uncharacterized unconventional
Tagcloud (Intersection) ?