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TRAF4 and GPRASP1
Number of citations of the paper that reports this interaction (PMID
16969126
)
5
Data Source:
BioGRID
(two hybrid)
TRAF4
GPRASP1
Gene Name
TNF receptor-associated factor 4
G protein-coupled receptor associated sorting protein 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Cytoskeleton
Plasma Membrane
Tight Junction
Perinuclear Region Of Cytoplasm
Cytoplasm
Molecular Function
DNA Binding
Ubiquitin-protein Transferase Activity
Tumor Necrosis Factor Receptor Binding
Protein Binding
Zinc Ion Binding
Protein Kinase Binding
Ubiquitin Protein Ligase Binding
Thioesterase Binding
WW Domain Binding
Protein Binding
Biological Process
Apoptotic Process
Signal Transduction
Activation Of NF-kappaB-inducing Kinase Activity
Respiratory Gaseous Exchange
Protein Ubiquitination
Respiratory Tube Development
Regulation Of Apoptotic Process
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of JNK Cascade
Positive Regulation Of Protein Homodimerization Activity
Endosome To Lysosome Transport
G-protein Coupled Receptor Catabolic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
69 interactors:
ALKBH4
ARNT2
BAHD1
BANP
BCKDK
BCL6B
BYSL
CALCOCO2
CBL
CBLC
CCHCR1
CENPE
CHUK
DTX3
EXOC7
FBXL18
FTH1
GORASP2
GPRASP1
HOMEZ
IRAK1
ISYNA1
KANSL1
KDM1A
KRT31
KRT40
LTBR
MAGED1
MAP3K4
MRPL28
NCF1
NGFR
NGFRAP1
NOS1AP
NPAS2
PDE4DIP
PKD1P1
PLSCR1
PSMC3
QARS
REXO1L6P
RNF114
RPS6KB1
SIGLEC7
SMURF1
SMURF2
SORBS2
SPDL1
SUMO1
TARBP2
TBC1D7
TBC1D8
TGFB1I1
TICAM1
TNFRSF4
TP53BP2
TRAF6
TRIM37
TYK2
UBE2I
UBL4A
UBL4B
USP7
WBP11
WWP1
WWP2
ZNF3
ZNF512B
ZNF581
47 interactors:
ADRB1
ADRB2
AGTR1
ATXN7
C8orf33
CALCR
CHRM1
CHRM2
CHRM3
CHRM4
CHRM5
CRIP1
CXCR2
F2R
F2RL1
GLP1R
GLYAT
GRM1
GRM5
GRM8
HGH1
HMOX2
HTR7
LAMTOR5
LRP2
MAP7D1
MLNR
MTF2
OFD1
OPRD1
OPRK1
OPRL1
OPRM1
OXTR
PBK
PER1
PFDN1
SNAPIN
STMN2
TAC3
TACR1
TACR2
TACR3
TBXA2R
TFG
TRAF4
VIPR1
Entrez ID
9618
9737
HPRD ID
03915
02333
Ensembl ID
ENSG00000076604
ENSG00000198932
Uniprot IDs
Q9BUZ4
Q5JY77
PDB IDs
2EOD
2YUC
4M4E
Enriched GO Terms of Interacting Partners
?
Protein Modification By Small Protein Conjugation
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Protein Ubiquitination
Regulation Of Gene Expression
Regulation Of Signal Transduction
Regulation Of Metabolic Process
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Nucleic Acid-templated Transcription
Regulation Of Signaling
Regulation Of RNA Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Transcription, DNA-templated
Response To Growth Factor
Regulation Of Protein Metabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Ubiquitin-dependent SMAD Protein Catabolic Process
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Signal Transduction
Cellular Protein Modification Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Cellular Protein Metabolic Process
Negative Regulation Of Biosynthetic Process
Regulation Of Cellular Protein Metabolic Process
Cellular Response To Growth Factor Stimulus
Regulation Of Innate Immune Response
Negative Regulation Of Transcription, DNA-templated
Response To Organic Substance
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Programmed Cell Death
Proteolysis Involved In Cellular Protein Catabolic Process
Response To Cytokine
Cellular Protein Catabolic Process
Cell Death
Death
Protein Metabolic Process
Cellular Response To Organic Substance
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of NF-kappaB Transcription Factor Activity
Neurotrophin TRK Receptor Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
TRIF-dependent Toll-like Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Positive Regulation Of Cellular Protein Metabolic Process
Protein Catabolic Process
G-protein Coupled Receptor Signaling Pathway
Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Positive Regulation Of Cytosolic Calcium Ion Concentration
Synaptic Transmission
Cytosolic Calcium Ion Homeostasis
Regulation Of Smooth Muscle Contraction
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
Cell Surface Receptor Signaling Pathway
Cellular Calcium Ion Homeostasis
Calcium Ion Homeostasis
Cellular Response To Stimulus
Cellular Metal Ion Homeostasis
Cell-cell Signaling
Positive Regulation Of Smooth Muscle Contraction
Cellular Cation Homeostasis
Cellular Ion Homeostasis
Signaling
Signal Transduction
Metal Ion Homeostasis
Cell Communication
Blood Circulation
Cellular Chemical Homeostasis
Ion Homeostasis
Response To Stimulus
Neuropeptide Signaling Pathway
Regulation Of Muscle Contraction
G-protein Coupled Acetylcholine Receptor Signaling Pathway
Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Cellular Homeostasis
Chemical Homeostasis
Regulation Of Blood Pressure
Tachykinin Receptor Signaling Pathway
Regulation Of Systemic Arterial Blood Pressure
Opioid Receptor Signaling Pathway
Regulation Of Vasoconstriction
Positive Regulation Of Uterine Smooth Muscle Contraction
Neurological System Process
Homeostatic Process
Regulation Of Cellular Process
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Blood Pressure
Behavior
Regulation Of CAMP Biosynthetic Process
Sensory Perception Of Pain
Regulation Of Secretion
Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G-protein Coupled Signaling Pathway
Regulation Of CAMP Metabolic Process
Response To Abiotic Stimulus
Regulation Of Adenylate Cyclase Activity
Tagcloud
?
bcr
cart
cd40
cd54
cd95
ciap2
define
dr3
driven
effector
engagement
fas
icam
linking
mapk
mapkapk
minimal
p38
permeable
perturbed
potentiating
requirement
responsive
sb203580
selectively
stimulates
tonsillar
traf1
unaffected
Tagcloud (Difference)
?
bcr
cart
cd40
cd54
cd95
ciap2
define
dr3
driven
effector
engagement
fas
icam
linking
mapk
mapkapk
minimal
p38
permeable
perturbed
potentiating
requirement
responsive
sb203580
selectively
stimulates
tonsillar
traf1
unaffected
Tagcloud (Intersection)
?