HAND2 and CENPB

Number of citations of the paper that reports this interaction (PMID 11812799)
10

Data Source:
HPRD (two hybrid)

		HAND2	CENPB
Gene Name		heart and neural crest derivatives expressed 2	centromere protein B, 80kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Transcription Factor Complex Protein Complex	Chromosome, Centromeric Region Nucleus Chromosome
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription AT DNA Binding Transcription Coactivator Activity Protein Binding Transcription Factor Binding Activating Transcription Factor Binding Protein Homodimerization Activity Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity E-box Binding	Chromatin Binding Satellite DNA Binding Centromeric DNA Binding Sequence-specific DNA Binding
	Biological Process	Angiogenesis In Utero Embryonic Development Heart Looping Suckling Behavior Heart Morphogenesis Cardiac Right Ventricle Formation Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Regulation Of Secondary Heart Field Cardioblast Proliferation Apoptotic Process Involved In Heart Morphogenesis Noradrenergic Neuron Differentiation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Apoptotic Process Heart Development Adult Heart Development Mesenchymal Cell Proliferation Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Neural Crest Cell Development Odontogenesis Of Dentin-containing Tooth Embryonic Digit Morphogenesis Negative Regulation Of DNA Binding Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Tongue Development Negative Regulation Of Osteoblast Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Sympathetic Nervous System Development Thymus Development Peripheral Nervous System Neuron Development Palate Development Cartilage Morphogenesis Coronary Artery Morphogenesis Visceral Serous Pericardium Development Cardiac Neural Crest Cell Development Involved In Outflow Tract Morphogenesis Cell Proliferation Involved In Outflow Tract Morphogenesis Positive Regulation Of Transcription Regulatory Region DNA Binding Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Norepinephrine Biosynthetic Process Positive Regulation Of Semaphorin-plexin Signaling Pathway Involved In Outflow Tract Morphogenesis	Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: CENPB COPS5 EP300 GATA4 HAND1 HEY2 HEYL NPM1 PHOX2A PPP2R5D PRKACA PRKCA TCF3 TCF4	17 interactors: ANXA7 APP CDKN1A CSNK2B FBXO25 GADD45A GFI1B GSK3B HAND2 NR3C1 PARP1 PARP2 PIN1 RPS6KA6 SMN1 TAC1 TK1
Entrez ID		9464	1059
HPRD ID		03872	00314
Ensembl ID		ENSG00000164107	ENSG00000125817
Uniprot IDs		P61296	P07199
PDB IDs			1BW6 1HLV 1UFI
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Metabolic Process Muscle Structure Development Positive Regulation Of Transcription, DNA-templated Cardiovascular System Development Regulation Of Nitrogen Compound Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Cellular Metabolic Process Cardiac Septum Morphogenesis Anatomical Structure Formation Involved In Morphogenesis Cardiac Ventricle Morphogenesis Tissue Development Anatomical Structure Morphogenesis Cardiac Right Ventricle Morphogenesis Atrioventricular Valve Morphogenesis Regulation Of Metabolic Process Cardiac Septum Development Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Atrioventricular Valve Development Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Binding Positive Regulation Of Dense Core Granule Biogenesis Cardiac Ventricle Development Regulation Of Cell Cycle Organ Development Striated Muscle Tissue Development Heart Valve Morphogenesis Heart Valve Development Muscle Tissue Development Transcription, DNA-templated Histone H3-T6 Phosphorylation Tissue Morphogenesis Epithelium Development System Development Energy Reserve Metabolic Process Cardiac Chamber Development RNA Biosynthetic Process Developmental Process Regulation Of Transcription, DNA-templated Embryo Development Regulation Of Nucleic Acid-templated Transcription Tube Development Regulation Of RNA Biosynthetic Process Regulation Of Heart Contraction	Regulation Of Binding Negative Regulation Of Phosphorylation Regulation Of Signaling Anatomical Structure Development Cellular Metabolic Process Response To External Stimulus Positive Regulation Of Transcription Regulatory Region DNA Binding Regulation Of Phosphorylation Response To Organic Substance System Development Positive Regulation Of Cellular Metabolic Process Response To Stress Regulation Of DNA Binding Response To Hormone Apoptotic Process Regulation Of Signal Transduction Regulation Of Phosphorus Metabolic Process Signal Transduction In Response To DNA Damage Negative Regulation Of Cellular Metabolic Process Developmental Process Behavior Programmed Cell Death Cell Death Death Regulation Of Protein Phosphorylation Response To Abiotic Stimulus Multicellular Organismal Development Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Binding Tube Development Positive Regulation Of Protein Phosphorylation Suckling Behavior Regulation Of Protein Kinase Activity Cellular Protein Modification Process Regulation Of Transcription Regulatory Region DNA Binding Positive Regulation Of Protein Metabolic Process Axon Guidance Protein ADP-ribosylation Regulation Of Kinase Activity Response To Glucocorticoid Signal Transduction Negative Regulation Of MAPK Cascade Positive Regulation Of Metabolic Process Response To Corticosteroid Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Import Into Nucleus Cellular Response To DNA Damage Stimulus Positive Regulation Of Phosphorylation Response To Organic Cyclic Compound Response To Inorganic Substance
Tagcloud ?		absent adenocarcinoma adenocarcinomas archival atypia atypical benign crest diagnoses disordered embedded endometrial endometrioid endometrium exact helix hyperplasia hysterectomy lost moderate paraffin prevents progesterone proliferative simple stroma stromal suppress weak	agreement altman asian bland cenpa cohen fibrillarin iif immunoassay interstitial kappa ku lia limits nc ncs nor90 oa outside plots pmscl100 ro52 ro60 rp155 sle ssc stored telangiectasia utility
Tagcloud (Difference) ?		absent adenocarcinoma adenocarcinomas archival atypia atypical benign crest diagnoses disordered embedded endometrial endometrioid endometrium exact helix hyperplasia hysterectomy lost moderate paraffin prevents progesterone proliferative simple stroma stromal suppress weak	agreement altman asian bland cenpa cohen fibrillarin iif immunoassay interstitial kappa ku lia limits nc ncs nor90 oa outside plots pmscl100 ro52 ro60 rp155 sle ssc stored telangiectasia utility
Tagcloud (Intersection) ?