FATE1 and BIK

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FATE1	BIK
Gene Name		fetal and adult testis expressed 1	BCL2-interacting killer (apoptosis-inducing)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Integral Component Of Membrane	Endomembrane System Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding	Protein Binding Protein Heterodimerization Activity BH Domain Binding
	Biological Process		Apoptotic Process Spermatogenesis Male Gonad Development Apoptotic Mitochondrial Changes Positive Regulation Of Protein Homooligomerization Positive Regulation Of Release Of Cytochrome C From Mitochondria
Pathways
Drugs
Diseases
GWAS			Prostate cancer ( 21743057)
Protein-Protein Interactions		49 interactors: AGTRAP AQP9 BCL2L2 BIK BNIP2 BNIP3 BNIP3L BSND BTN2A2 CCDC155 CCDC70 CD302 CD79A CSF2RA DCTN5 EMD GPR25 INPP5K KCNS2 LNPEP MARCH2 MARCH5 MR1 NDUFB11 NRG4 NRSN1 PIN4 PRRG2 RNF183 RPRM SEC22A SEC22C SEC23B SLC38A1 SLC7A1 SNAP47 SYNDIG1 SYNE4 SYNGR1 SYNPR TBP TIMMDC1 TM4SF4 TMEM74 TRAF2 TRAF3IP3 USHBP1 USP20 YIPF4	11 interactors: APP BCL2 BCL2A1 BCL2L1 BCL2L2 CRKL FATE1 MCL1 NR2F2 SOCS3 TANK
Entrez ID		89885	638
HPRD ID		02346	04547
Ensembl ID		ENSG00000147378	ENSG00000100290
Uniprot IDs		Q969F0	Q13323
PDB IDs			2IPE
Enriched GO Terms of Interacting Partners?		Mitochondrial Protein Catabolic Process Membrane Organization Vesicle Fusion With Golgi Apparatus Vesicle Fusion Positive Regulation Of Mitochondrial Fission Mitochondrial Outer Membrane Permeabilization Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrial Fission Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Apoptotic Mitochondrial Changes Organelle Fusion Positive Regulation Of Mitochondrial Membrane Permeability Regulation Of Mitochondrion Organization ER To Golgi Vesicle-mediated Transport Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Transport Positive Regulation Of Release Of Cytochrome C From Mitochondria Membrane Fusion Establishment Of Localization In Cell Regulation Of Mitochondrial Membrane Permeability Chromosome Localization To Nuclear Envelope Involved In Synapsis Positive Regulation Of Renal Water Transport Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Cellular Localization Regulation Of Membrane Permeability Protein Autoubiquitination	Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Intracellular Signal Transduction Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Anoikis Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Anoikis Intracellular Signal Transduction Apoptotic Signaling Pathway Response To Stress Signal Transduction Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Signaling Negative Regulation Of Programmed Cell Death Cell Communication Apoptotic Process Reproductive Structure Development Negative Regulation Of Cell Death Reproductive System Development Intracellular Receptor Signaling Pathway Programmed Cell Death Regulation Of Intracellular Signal Transduction Cell Death Regulation Of Signal Transduction Neuron Apoptotic Process Death Negative Regulation Of Signal Transduction Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Neuron Death Negative Regulation Of Signaling Apoptotic Mitochondrial Changes Regulation Of Signaling Cellular Response To Stimulus Cell Surface Receptor Signaling Pathway Reproductive Process Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Developmental Process Involved In Reproduction Regulation Of Apoptotic Process Sexual Reproduction Innate Immune Response Cellular Response To Stress Cellular Response To DNA Damage Stimulus Regulation Of Cell Death Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Response To Stimulus
Tagcloud ?			abt actinomycin antagonism antagonizing bak bcl bh3 carfilzomib concurrent crc cyclohexamide ectopic ectopically enabled irreversible isogenic kras mimetic noxa overcome potently sensitized sequestered shrna synergistic synergistically synergy ultimately xl
Tagcloud (Difference) ?			abt actinomycin antagonism antagonizing bak bcl bh3 carfilzomib concurrent crc cyclohexamide ectopic ectopically enabled irreversible isogenic kras mimetic noxa overcome potently sensitized sequestered shrna synergistic synergistically synergy ultimately xl
Tagcloud (Intersection) ?