EED and ITGAE

Number of citations of the paper that reports this interaction (PMID 9765275)
13

Data Source:
HPRD (two hybrid)

		EED	ITGAE
Gene Name		embryonic ectoderm development	integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Sex Chromatin Nucleus Nucleoplasm Nucleolus Cytoplasm ESC/E(Z) Complex Pronucleus	Plasma Membrane Integrin Complex External Side Of Plasma Membrane
	Molecular Function	Chromatin Binding Protein Binding Histone Methyltransferase Activity Identical Protein Binding	Metal Ion Binding
	Biological Process	Regulation Of Gene Expression By Genetic Imprinting Transcription, DNA-templated Gene Expression Histone Methylation Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Histone H3-K27 Methylation	Cell Adhesion Integrin-mediated Signaling Pathway Extracellular Matrix Organization
Pathways		Oxidative Stress Induced Senescence Cellular Senescence Epigenetic regulation of gene expression PRC2 methylates histones and DNA	Integrin cell surface interactions
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder ( 18839057)
Protein-Protein Interactions		38 interactors: AEBP2 ANXA5 BRCA1 CDK2AP2 CTSL DNMT1 DNMT3A DNMT3B DUSP23 EHMT1 EPC2 EZH1 EZH2 FHL1 HDAC1 HDAC2 HDAC3 HIST1H1A HIST1H3A ITGA4 ITGAE ITGB7 MAP1LC3B NUDT21 PINK1 PJA1 PPP1CA PPP1R8 RBBP4 RPS10 SELENBP1 SMYD3 TGS1 TSC22D1 UBE2W YY1 ZBED8 ZFP42	4 interactors: CDH1 CHFR EED ITGB7
Entrez ID		8726	3682
HPRD ID		09343	05249
Ensembl ID		ENSG00000074266	ENSG00000083457
Uniprot IDs		E9PJK2 O75530	P38570
PDB IDs		3IIW 3IIY 3IJ0 3IJ1 3IJC 3JPX 3JZG 3JZH 3JZN 3K26 3K27
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression, Epigenetic Regulation Of Gene Expression, Epigenetic Chromatin Organization Chromosome Organization Chromatin Modification Negative Regulation Of Gene Expression DNA Methylation DNA Methylation On Cytosine Organelle Organization Negative Regulation Of Transcription, DNA-templated DNA Modification Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Methylation Negative Regulation Of Transcription From RNA Polymerase II Promoter C-5 Methylation Of Cytosine Nucleobase-containing Compound Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Transcription, DNA-templated Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Histone H3-K9 Methylation Histone H3-K27 Methylation DNA Metabolic Process Chromatin Silencing Histone H3-K9 Modification Transcription, DNA-templated Gene Silencing Positive Regulation Of Histone H3-K4 Methylation Regulation Of Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Histone Modification Negative Regulation Of Histone Methylation Cell-matrix Adhesion Involved In Ameboidal Cell Migration Histone H4 Deacetylation Cellular Metabolic Process Regulation Of Histone H3-K4 Methylation Cellular Macromolecule Biosynthetic Process Circadian Regulation Of Gene Expression RNA Metabolic Process Macromolecule Biosynthetic Process	Protein Polyubiquitination Cell-matrix Adhesion Involved In Ameboidal Cell Migration Cell Cycle Checkpoint Cellular Response To Indole-3-methanol Mitotic Nuclear Division Activation Of Anaphase-promoting Complex Activity Salivary Gland Cavitation Protein Localization To Membrane Extracellular Matrix Organization Extracellular Structure Organization Positive Regulation Of Histone H3-K27 Methylation Cell Division Regulation Of Histone H3-K27 Methylation Leukocyte Tethering Or Rolling Negative Regulation Of Cell Aging Ubiquitin-dependent Protein Catabolic Process T Cell Migration Modification-dependent Protein Catabolic Process Regulation Of Branching Involved In Salivary Gland Morphogenesis Intestinal Epithelial Cell Development Single Organismal Cell-cell Adhesion Cellular Response To Lithium Ion Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Regulation Of Protein Localization To Cell Surface Regulation Of Water Loss Via Skin Protein Ubiquitination Intestinal Epithelial Cell Differentiation Heterotypic Cell-cell Adhesion Protein K11-linked Ubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Trophectodermal Cell Differentiation Regulation Of Gene Expression By Genetic Imprinting Lymphocyte Migration Mitotic Cell Cycle Process Cellular Extravasation Response To Lithium Ion Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cell Morphogenesis Involved In Differentiation Mitotic Cell Cycle G2 DNA Damage Checkpoint Genetic Imprinting Lens Fiber Cell Differentiation Positive Regulation Of Histone Methylation Positive Regulation Of Transcription Factor Import Into Nucleus Blastocyst Formation Viral Entry Into Host Cell Regulation Of Meiosis Entry Into Host Cell
Tagcloud ?		70z bait cdnas coexpressed coimmunoprecipitated compositions confirming developmentally drosophila ectoderm esc ezh2 fragment gal4 homolog hybrid hypomorphic lethal mammalian polycomb repeats represses repressor silenced t1031a t1040c wd40 yeast zeste	angptl4 atp5d atp5g3 atp5j2 atp5l ccnb1 cdc10 cdc20 cdc23 dyn efemp1 eng epas1 fbn1 fn1 hcaecs hmox1 itga5 itgav lamr1 lgals3 loxl2 lss p4hb pgk1 pkd2 sage vasodilatory vasoreactive
Tagcloud (Difference) ?		70z bait cdnas coexpressed coimmunoprecipitated compositions confirming developmentally drosophila ectoderm esc ezh2 fragment gal4 homolog hybrid hypomorphic lethal mammalian polycomb repeats represses repressor silenced t1031a t1040c wd40 yeast zeste	angptl4 atp5d atp5g3 atp5j2 atp5l ccnb1 cdc10 cdc20 cdc23 dyn efemp1 eng epas1 fbn1 fn1 hcaecs hmox1 itga5 itgav lamr1 lgals3 loxl2 lss p4hb pgk1 pkd2 sage vasodilatory vasoreactive
Tagcloud (Intersection) ?