Gene Name |
small ubiquitin-like modifier 1 |
estrogen receptor 1 |
Image |
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Gene Ontology Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- Diethylstilbestrol
- Chlorotrianisene
- Conjugated Estrogens
- Etonogestrel
- Desogestrel
- Levonorgestrel
- Progesterone
- Raloxifene
- Toremifene
- Medroxyprogesterone
- Estrone
- Tamoxifen
- Estradiol
- Ethynodiol Diacetate
- Clomifene
- Dienestrol
- Fulvestrant
- Norgestimate
- Ethinyl Estradiol
- Melatonin
- Trilostane
- Naloxone
- Fluoxymesterone
- Estramustine
- Mestranol
- Danazol
- Allylestrenol
- Genistein
- Compound 19
- Compound 18
- Compound 4-D
- 1-[4-(Octahydro-Pyrido[1,2-a]Pyrazin-2-Yl)-Phenyl]-2-Phenyl-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol
- 2-Phenyl-1-[4-(2-Piperidin-1-Yl-Ethoxy)-Phenyl]-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol
- Estriol
- Estropipate
- Quinestrol
- Ospemifene
- 17-METHYL-17-ALPHA-DIHYDROEQUILENIN
- 4-(2-amino-1-methyl-1H-imidazo[4,5-b]pyridin-6-yl)phenol
- [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE
- 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-8-METHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
- 4-[(1S,2S,5S,9R)-5-(HYDROXYMETHYL)-8,9-DIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
- 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-6,8,9-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
- (2R,3R,4S)-3-(4-HYDROXYPHENYL)-4-METHYL-2-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]CHROMAN-6-OL
- (3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL
- (9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL
- (9BETA,11ALPHA,13ALPHA,14BETA,17ALPHA)-11-(METHOXYMETHYL)ESTRA-1(10),2,4-TRIENE-3,17-DIOL
- 3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL
- 3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL
- dimethyl (1R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate
- (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL
- N-[(1R)-3-(4-HYDROXYPHENYL)-1-METHYLPROPYL]-2-(2-PHENYL-1H-INDOL-3-YL)ACETAMIDE
- (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL
- 4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol
- 4-(6-HYDROXY-1H-INDAZOL-3-YL)BENZENE-1,3-DIOL
- DIETHYL (1R,2S,3R,4S)-5,6-BIS(4-HYDROXYPHENYL)-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXYLATE
- 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE
- 4-[(1S,2R,5S)-4,4,8-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
- (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-9-OL
- RALOXIFENE CORE
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Diseases |
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GWAS |
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Protein-Protein Interactions |
194 interactors:
ADD3
APP
AR
ARL13A
ATF2
ATF3
ATXN1
ATXN3
ATXN7
AURKA
AURKB
BCAM
BCL11A
BIRC3
BLM
BRCA1
C11orf65
C18orf25
CAMSAP2
CARD9
CASP2
CASP8
CCDC67
CD40
CDCA8
CHAF1A
CHD3
CHD4
COG1
CTNNA1
DAXX
DDX24
DNM1
DNMT3A
DNMT3B
DTX2
EDARADD
ESR1
ETV1
ETV4
ETV6
FADD
FAM118B
FANCM
FAS
FASLG
FBF1
FLI1
FOS
FOXL2
FOXM1
GATA1
GLP1R
GMCL1
HDAC4
HDAC9
HGS
HIF1A
HIPK2
HIPK3
HIRA
HNF4A
HNRNPC
HNRNPK
HSF1
HSF2
HTT
ING2
IRAK1
JUN
KAT2A
KAT6B
KDM1A
KRT14
KRT18
KRT5
KRT8
MAP2K1
MAPK1IP1L
MDC1
MDM2
MECOM
MEF2A
MEF2C
MITF
MKL1
MSX1
MUL1
MX1
MYB
NCOA1
NCOA2
NCOA3
NCOR2
NELFE
NFE2L2
NFKBIA
NIN
NOS1
NOX5
NR3C1
NR3C2
PARK7
PARP1
PAX6
PDGFC
PHC1
PIAS1
PIAS2
PIAS3
PIAS4
PIK3C3
PLK3
PML
PPARA
PPM1J
RAD51
RAD52
RAD54B
RAD54L2
RANBP2
RANGAP1
RB1
RBM25
RHOXF2
RNF4
RPS3
SAE1
SALL1
SART1
SATB1
SEMA6A
SENP1
SENP2
SENP6
SETX
SH3KBP1
SLC2A1
SOX10
SOX2
SOX6
SP1
SP100
SP3
SREBF1
SREBF2
SSRP1
STAB2
STK24
STMN2
SUMO1P1
SUMO2
SUPT7L
SYMPK
TCERG1
TCF4
TDG
TDP2
TFCP2
TGM2
TNFRSF1A
TOE1
TOP1
TOP2A
TOP2B
TOPORS
TP53
TP73
TRAF4
TRIM24
TRIM5
TRPS1
TSC22D3
TSHZ2
TSNAX
UBA2
UBE2I
USP25
USP7
USPL1
WNK1
WRN
XRCC1
XRCC5
ZBTB16
ZBTB26
ZBTB6
ZBTB7A
ZCCHC12
ZCCHC7
ZMYM2
ZMYM5
ZNF24
ZNF451
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266 interactors:
ACTN4
AHR
AKAP13
AKT1
AKT2
AR
ARHGEF15
ARNT
ATAD2
BAG1
BCAR1
BCAS2
BDNF
BRCA1
BTF3
CALM1
CALM2
CALM3
CAV1
CBLL1
CCNC
CCND1
CCNH
CCNT1
CDC25B
CDK2
CDK7
CDK8
CDKN1A
CEBPA
CEBPB
CHD9
CHUK
CITED1
COPS5
CREBBP
CSNK2B
CTNNB1
CUEDC2
CUL4B
DAP3
DDX5
DDX54
DNTTIP2
DUT
EGFR
EHMT2
EIF3I
EP300
ERBB2
ESR2
ESRRA
FHL2
FKBP4
FKBP5
FLII
FOXO1
FOXO3
FOXO4
GADD45B
GADD45G
GNAI1
GNAI2
GNAI3
GRB2
GRIP1
GTF2B
GTF2H1
HDAC4
HDAC5
HDAC9
HEXIM1
HNF4A
HSP90AA1
HSP90AB1
HSPA4
HSPA8
IGF1R
ING1
ISL1
ITGB3BP
JUN
JUNB
JUND
KAT5
KDM5A
KIF1A
KLF5
KMT2D
LCK
LCOR
LDB1
LINC00312
LRIF1
MAPK1
MAPK14
MAPK3
MDM2
MED1
MED10
MED12
MED13
MED14
MED16
MED17
MED20
MED21
MED23
MED24
MED25
MED6
MED7
MEN1
MGMT
MKNK2
MMS19
MNAT1
MPG
MSH2
MTA1
MTA2
MTA3
MTCH2
MUC1
MVP
NCOA1
NCOA2
NCOA3
NCOA4
NCOA6
NCOA7
NCOR1
NCOR2
NELFB
NFKB1
NPPA
NR0B1
NR0B2
NR1H4
NR2C1
NR2C2
NR2F1
NR2F6
NRIP1
NSD1
OTUB1
PAGR1
PAK1
PAK6
PELP1
PGC
PGR
PHB
PHB2
PIAS1
PIAS2
PIAS3
PIK3R1
PIK3R3
PNRC2
POLR1B
POLR2D
POU2F1
POU2F2
POU4F1
POU4F2
PPARG
PPARGC1A
PPARGC1B
PPID
PRDM2
PRKACA
PRMT1
PRMT2
PRPF6
PSMC5
PTEN
PTGES3
PTMA
PTPN1
PTPN6
RAC3
RANBP9
RARA
RBBP4
RBBP7
RBFOX2
RBM23
RBM39
RELA
REXO4
RFX4
RGS3
RLIM
RNF14
RNF4
RPS6KA1
RPS6KA3
RXRA
SAFB
SAFB2
SETD7
SF1
SHC1
SKIL
SKP2
SLC30A9
SMAD2
SMAD3
SMAD4
SMARCA2
SMARCA4
SMARCD1
SMARCD3
SMARCE1
SMURF1
SMYD2
SOS1
SP1
SP3
SRA1
SRC
SREBF1
STAT5A
STRN
STUB1
SUMO1
SUV39H1
SUV420H1
SVIL
TAB2
TADA3
TAF10
TAF1A
TAF1B
TAF2
TAP1
TBP
TCF20
TDG
THRA
THRB
TNFRSF14
TP53
TRAM1
TRIM24
TRIM25
TRIM28
TRIM59
TRIP4
TRRAP
TSC2
TUBA1B
TUBB
UBE2I
UIMC1
USF1
VAV3
WHSC1
WIPI1
XBP1
YWHAH
YWHAQ
ZBTB16
ZBTB17
ZNF398
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Entrez ID |
7341 |
2099 |
HPRD ID |
03554 |
00589 |
Ensembl ID |
ENSG00000116030
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ENSG00000091831
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Uniprot IDs |
P63165
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G4XH65
P03372
Q9UBT1
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PDB IDs |
1A5R
1TGZ
1WYW
1Y8R
1Z5S
2ASQ
2BF8
2G4D
2IO2
2IY0
2IY1
2KQS
2LAS
2PE6
2UYZ
2VRR
3KYC
3KYD
3RZW
3UIP
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1A52
1AKF
1ERE
1ERR
1G50
1GWQ
1GWR
1HCP
1HCQ
1L2I
1PCG
1QKT
1QKU
1R5K
1SJ0
1UOM
1X7E
1X7R
1XP1
1XP6
1XP9
1XPC
1XQC
1YIM
1YIN
1ZKY
2AYR
2B1V
2B1Z
2B23
2BJ4
2FAI
2G44
2G5O
2I0J
2IOG
2IOK
2JF9
2JFA
2LLO
2LLQ
2OCF
2OUZ
2P15
2POG
2Q6J
2Q70
2QA6
2QA8
2QAB
2QE4
2QGT
2QGW
2QH6
2QR9
2QSE
2QXM
2QXS
2QZO
2R6W
2R6Y
2YAT
2YJA
3CBM
3CBO
3CBP
3DT3
3ERD
3ERT
3HLV
3HM1
3L03
3OS8
3OS9
3OSA
3Q95
3Q97
3UU7
3UUA
3UUC
3UUD
4AA6
4DMA
4IU7
4IUI
4IV2
4IV4
4IVW
4IVY
4IW6
4IW8
4IWC
4IWF
4JC3
4JDD
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
aphidicolin
attachment
break
breakage
budding
cfs
covalent
excessive
fields
fragile
hallmark
modifier
ortholog
perturbed
pol32
pold3
polypeptides
proteomic
recombinational
replication
resource
rpa
ssdna
stresses
subfamily
sumo2
sumo3
sumoylation
|
analyzing
brca1
carcinogenic
changed
characters
coactivator
concordant
conduct
differentiationassociated
discovered
downloaded
e2
enrichment
estradiol
go
gses9623
gsm986085
gsm986087
guidance
macs
mcf7
omnibus
ontology
p300bound
p300regulated
participated
peakcalling
software
theoretical
|
Tagcloud (Difference) ? |
aphidicolin
attachment
break
breakage
budding
cfs
covalent
excessive
fields
fragile
hallmark
modifier
ortholog
perturbed
pol32
pold3
polypeptides
proteomic
recombinational
replication
resource
rpa
ssdna
stresses
subfamily
sumo2
sumo3
sumoylation
|
analyzing
brca1
carcinogenic
changed
characters
coactivator
concordant
conduct
differentiationassociated
discovered
downloaded
e2
enrichment
estradiol
go
gses9623
gsm986085
gsm986087
guidance
macs
mcf7
omnibus
ontology
p300bound
p300regulated
participated
peakcalling
software
theoretical
|
Tagcloud (Intersection) ? |
|