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TNNT1 and TNNI2
Number of citations of the paper that reports this interaction (PMID
9448267
)
8
Data Source:
HPRD
(two hybrid, in vivo, in vitro)
TNNT1
TNNI2
Gene Name
troponin T type 1 (skeletal, slow)
troponin I type 2 (skeletal, fast)
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Troponin Complex
Nucleus
Cytosol
Troponin Complex
Molecular Function
Tropomyosin Binding
Troponin T Binding
Actin Binding
Protein Binding
Troponin T Binding
Biological Process
Skeletal Muscle Contraction
Muscle Filament Sliding
Slow-twitch Skeletal Muscle Fiber Contraction
Negative Regulation Of Muscle Contraction
Skeletal Muscle Contraction
Regulation Of Muscle Contraction
Muscle Filament Sliding
Positive Regulation Of Transcription, DNA-templated
Pathways
Striated Muscle Contraction
Striated Muscle Contraction
Drugs
Diseases
GWAS
Inflammatory bowel disease (
23128233
)
Protein-Protein Interactions
61 interactors:
ARMC8
BLOC1S2
BMPR1B
C2orf44
CCDC136
CCDC85B
CHD3
DDX5
EEF1G
FAF1
FXR2
FYN
HAP1
HMGXB4
HMP19
HSP90AB1
IMMT
KAT5
KRT40
LARP1
LDOC1
MARS
MORF4L1
NACAD
NAGK
NFE2L2
NINL
OSBP2
OSM
PI4KA
PLEKHF1
PNMA1
PPFIA1
PRKG1
PSMC5
SEC31A
SERPINA4
SH3GL3
SMAD1
SMAD2
SMURF1
SNW1
TBPL1
TFIP11
TGFBR1
TMEM98
TNNC1
TNNI1
TNNI2
TNNI3
TPM1
TPM3
TRA2A
TRIM63
UBE2D1
VIM
ZC3H15
ZKSCAN5
ZMYND19
ZNF250
ZNF768
13 interactors:
ACTB
CALM1
ESRRA
HNF4G
PKD2L1
RORB
TNNC1
TNNC2
TNNT1
TNNT3
TRIM55
TRIM63
UPF2
Entrez ID
7138
7136
HPRD ID
01841
01843
Ensembl ID
ENSG00000105048
ENSG00000130598
Uniprot IDs
P13805
P48788
PDB IDs
Enriched GO Terms of Interacting Partners
?
Muscle Filament Sliding
Actin-myosin Filament Sliding
Actin-mediated Cell Contraction
Actin Filament-based Movement
Muscle System Process
Regulation Of Metabolic Process
Muscle Contraction
Regulation Of Gene Expression
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Muscle Contraction
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Ventricular Cardiac Muscle Tissue Morphogenesis
Movement Of Cell Or Subcellular Component
Ventricular Cardiac Muscle Tissue Development
Regulation Of Cellular Process
Cardiac Muscle Tissue Morphogenesis
Signal Transduction
Regulation Of Transcription, DNA-templated
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Gene Expression
Cellular Response To Organic Substance
Muscle Tissue Morphogenesis
Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions
Regulation Of RNA Metabolic Process
Muscle Organ Morphogenesis
Cardiac Ventricle Morphogenesis
Cellular Macromolecule Biosynthetic Process
BMP Signaling Pathway
Positive Regulation Of Gene Expression
Macromolecule Biosynthetic Process
Signaling
Transcription, DNA-templated
Positive Regulation Of Cellular Metabolic Process
Striated Muscle Contraction
Positive Regulation Of Cellular Biosynthetic Process
Cell Communication
Cellular Response To Transforming Growth Factor Beta Stimulus
RNA Metabolic Process
RNA Biosynthetic Process
Response To Transforming Growth Factor Beta
Cardiac Muscle Tissue Development
Primary MiRNA Processing
Cellular Response To Stimulus
Regulation Of Cellular Component Organization
Positive Regulation Of Apoptotic Signaling Pathway
Response To Stimulus
Muscle Contraction
Skeletal Muscle Contraction
Actin-myosin Filament Sliding
Muscle Filament Sliding
Muscle System Process
Musculoskeletal Movement
Actin-mediated Cell Contraction
Regulation Of Muscle Contraction
Actin Filament-based Movement
Striated Muscle Contraction
Cellular Response To Steroid Hormone Stimulus
Response To Steroid Hormone
Steroid Hormone Mediated Signaling Pathway
Cellular Response To Organic Cyclic Compound
Hormone-mediated Signaling Pathway
Response To Lipid
Cellular Response To Lipid
Response To Organic Cyclic Compound
Response To Hormone
Transcription Initiation From RNA Polymerase II Promoter
Intracellular Receptor Signaling Pathway
Substantia Nigra Development
Cellular Response To Hormone Stimulus
Regulation Of ATPase Activity
DNA-templated Transcription, Initiation
Actin Filament-based Process
Neural Nucleus Development
Organ Development
Regulation Of Muscle Filament Sliding Speed
Movement Of Cell Or Subcellular Component
Regulation Of Striated Muscle Contraction
Midbrain Development
Detection Of Chemical Stimulus Involved In Sensory Perception Of Sour Taste
Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Regulation Of Muscle Filament Sliding
Diaphragm Contraction
Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity
Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation
Regulation Of Osteoblast Differentiation
Cellular Response To Organic Substance
Signal Transduction
Amacrine Cell Differentiation
Regulation Of High Voltage-gated Calcium Channel Activity
Sensory Perception Of Sour Taste
Involuntary Skeletal Muscle Contraction
System Development
Skeletal Muscle Atrophy
Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Response To Glucocorticoid
Tagcloud
?
apoc2
atp1a3
bckdha
cgb
cgm2
cyp2a
d19s112
d19s116
d19s117
d19s118
d19s119
d19s19
d19s2
d19s37
d19s50
d19s51
d19s54
d19s55
d19s6
d19s62
d19s63
d19s7
d19s8
d19s9
manb
pepd
prkcg
psg1
pw39
Tagcloud (Difference)
?
apoc2
atp1a3
bckdha
cgb
cgm2
cyp2a
d19s112
d19s116
d19s117
d19s118
d19s119
d19s19
d19s2
d19s37
d19s50
d19s51
d19s54
d19s55
d19s6
d19s62
d19s63
d19s7
d19s8
d19s9
manb
pepd
prkcg
psg1
pw39
Tagcloud (Intersection)
?