TNNT1 and LARP1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		TNNT1	LARP1
Gene Name		troponin T type 1 (skeletal, slow)	La ribonucleoprotein domain family, member 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Troponin Complex	Nucleoplasm Cytoplasm Membrane TORC1 Complex
	Molecular Function	Tropomyosin Binding Troponin T Binding	RNA Cap Binding MRNA 3'-UTR Binding Protein Binding Eukaryotic Initiation Factor 4E Binding Translation Activator Activity Translation Initiation Factor Binding Poly(A) RNA Binding MRNA 5'-UTR Binding
	Biological Process	Skeletal Muscle Contraction Muscle Filament Sliding Slow-twitch Skeletal Muscle Fiber Contraction Negative Regulation Of Muscle Contraction	Translational Initiation Cell Proliferation Positive Regulation Of Macroautophagy TOR Signaling Positive Regulation Of Translation
Pathways		Striated Muscle Contraction
Drugs
Diseases
GWAS
Protein-Protein Interactions		61 interactors: ARMC8 BLOC1S2 BMPR1B C2orf44 CCDC136 CCDC85B CHD3 DDX5 EEF1G FAF1 FXR2 FYN HAP1 HMGXB4 HMP19 HSP90AB1 IMMT KAT5 KRT40 LARP1 LDOC1 MARS MORF4L1 NACAD NAGK NFE2L2 NINL OSBP2 OSM PI4KA PLEKHF1 PNMA1 PPFIA1 PRKG1 PSMC5 SEC31A SERPINA4 SH3GL3 SMAD1 SMAD2 SMURF1 SNW1 TBPL1 TFIP11 TGFBR1 TMEM98 TNNC1 TNNI1 TNNI2 TNNI3 TPM1 TPM3 TRA2A TRIM63 UBE2D1 VIM ZC3H15 ZKSCAN5 ZMYND19 ZNF250 ZNF768	9 interactors: BCL2L1 CCDC155 CSNK2A1 SRPK1 TNNT1 YWHAB YWHAG YWHAQ YWHAZ
Entrez ID		7138	23367
HPRD ID		01841	11225
Ensembl ID		ENSG00000105048	ENSG00000155506
Uniprot IDs		P13805	Q6PKG0
PDB IDs
Enriched GO Terms of Interacting Partners?		Muscle Filament Sliding Actin-myosin Filament Sliding Actin-mediated Cell Contraction Actin Filament-based Movement Muscle System Process Regulation Of Metabolic Process Muscle Contraction Regulation Of Gene Expression Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Muscle Contraction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Ventricular Cardiac Muscle Tissue Morphogenesis Movement Of Cell Or Subcellular Component Ventricular Cardiac Muscle Tissue Development Regulation Of Cellular Process Cardiac Muscle Tissue Morphogenesis Signal Transduction Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Cellular Response To Organic Substance Muscle Tissue Morphogenesis Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions Regulation Of RNA Metabolic Process Muscle Organ Morphogenesis Cardiac Ventricle Morphogenesis Cellular Macromolecule Biosynthetic Process BMP Signaling Pathway Positive Regulation Of Gene Expression Macromolecule Biosynthetic Process Signaling Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Striated Muscle Contraction Positive Regulation Of Cellular Biosynthetic Process Cell Communication Cellular Response To Transforming Growth Factor Beta Stimulus RNA Metabolic Process RNA Biosynthetic Process Response To Transforming Growth Factor Beta Cardiac Muscle Tissue Development Primary MiRNA Processing Cellular Response To Stimulus Regulation Of Cellular Component Organization Positive Regulation Of Apoptotic Signaling Pathway Response To Stimulus	Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrion Organization Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Positive Regulation Of Apoptotic Signaling Pathway Apoptotic Signaling Pathway Regulation Of Organelle Organization Apoptotic Process Programmed Cell Death Cell Death Death Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Intracellular Transport Positive Regulation Of Cell Death Positive Regulation Of Signal Transduction Regulation Of Establishment Of Protein Localization Regulation Of Apoptotic Process Regulation Of Protein Localization Regulation Of Cell Death Membrane Organization Positive Regulation Of Organelle Organization Protein Targeting Regulation Of Intracellular Transport Intracellular Signal Transduction Regulation Of Cellular Localization Regulation Of Cellular Component Organization Establishment Of Localization In Cell Cellular Localization Germ Cell Development Positive Regulation Of Transport Intracellular Transport Regulation Of Signal Transduction Intracellular Protein Transport Cellular Response To Stimulus Cell Development Regulation Of Signaling Cell Cycle Process Anatomical Structure Development Chromosome Localization To Nuclear Envelope Involved In Synapsis Apoptotic Process In Bone Marrow Cell Differentiation Negative Regulation Of Cellular Metabolic Process Cellular Response To Organonitrogen Compound Signal Transduction Spermatogenesis Male Gamete Generation Developmental Process
Tagcloud ?		apoc2 atp1a3 bckdha cgb cgm2 cyp2a d19s112 d19s116 d19s117 d19s118 d19s119 d19s19 d19s2 d19s37 d19s50 d19s51 d19s54 d19s55 d19s6 d19s62 d19s63 d19s7 d19s8 d19s9 manb pepd prkcg psg1 pw39	acquires add3 annotation cdk4 comprehensive deregulated discovered exon intron isoforms make myriad phlpp2 portrait predominant prompt retention signatures skip splice spliced splicing sub switching systematically tailor tnbc transcriptome transcripts
Tagcloud (Difference) ?		apoc2 atp1a3 bckdha cgb cgm2 cyp2a d19s112 d19s116 d19s117 d19s118 d19s119 d19s19 d19s2 d19s37 d19s50 d19s51 d19s54 d19s55 d19s6 d19s62 d19s63 d19s7 d19s8 d19s9 manb pepd prkcg psg1 pw39	acquires add3 annotation cdk4 comprehensive deregulated discovered exon intron isoforms make myriad phlpp2 portrait predominant prompt retention signatures skip splice spliced splicing sub switching systematically tailor tnbc transcriptome transcripts
Tagcloud (Intersection) ?