BUB1 and AP3B1

Number of citations of the paper that reports this interaction (PMID 12419313)
4

Data Source:
HPRD (two hybrid)

		BUB1	AP3B1
Gene Name		BUB1 mitotic checkpoint serine/threonine kinase	adaptor-related protein complex 3, beta 1 subunit
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Condensed Nuclear Chromosome, Centromeric Region Nucleoplasm Cytoplasm Cytosol Membrane	Lysosomal Membrane Golgi Apparatus Membrane AP-3 Adaptor Complex Clathrin-coated Vesicle Membrane
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Protein Phosphatase Binding GTP-dependent Protein Binding
	Biological Process	Mitotic Cell Cycle Protein Phosphorylation Apoptotic Process Chromosome Segregation Regulation Of Sister Chromatid Cohesion Mitotic Nuclear Division Mitotic Cell Cycle Checkpoint Mitotic Spindle Assembly Checkpoint Cell Proliferation Viral Process Cell Division Regulation Of Chromosome Segregation Spindle Assembly Checkpoint Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Protein Targeting To Lysosome Intracellular Protein Transport Blood Coagulation Anterograde Axon Cargo Transport Melanosome Organization Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Anterograde Synaptic Vesicle Transport Positive Regulation Of NK T Cell Differentiation
Pathways		Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase	Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS			Insulin resistance/response ( 21901158)
Protein-Protein Interactions		18 interactors: AP1B1 AP2B1 AP3B1 AP4B1 APC ARIH2 BUB1B BUB3 CASC5 CDC20 CDK1 CRK EIF4EBP1 HDAC1 PLK1 RAE1 RDH12 SVIL	10 interactors: AP3S2 ARF1 ARF5 ARF6 ARR3 BUB1 BUB1B CLTC CSNK1A1 SLC30A3
Entrez ID		699	8546
HPRD ID		03907	04551
Ensembl ID		ENSG00000169679	ENSG00000132842
Uniprot IDs		B4DYG2 E9PC26 F5GXI5 O43683	E5RJ68 O00203
PDB IDs		2LAH 3E7E 4A1G
Enriched GO Terms of Interacting Partners?		Spindle Assembly Checkpoint Spindle Checkpoint Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Mitotic Cell Cycle Mitotic Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Regulation Of Mitotic Sister Chromatid Separation Cell Cycle Checkpoint Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Mitotic Cell Cycle Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Proteasomal Protein Catabolic Process Mitotic Cell Cycle Checkpoint Mitotic Nuclear Division Negative Regulation Of Cellular Protein Catabolic Process Regulation Of Chromosome Segregation Negative Regulation Of Cell Division Regulation Of Ubiquitin-protein Transferase Activity Protein Localization To Chromosome Negative Regulation Of Chromosome Organization Regulation Of Cell Cycle Cell Cycle Metaphase/anaphase Transition Of Mitotic Cell Cycle Negative Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Cell Division Cell Cycle Process Negative Regulation Of Cell Cycle Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Division Negative Regulation Of Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Mitotic Nuclear Division Protein Localization To Kinetochore Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Localization To Chromosome, Centromeric Region Negative Regulation Of Mitotic Cell Cycle Phase Transition Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Cellular Protein Localization Protein Catabolic Process Regulation Of Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Chromosome Organization Regulation Of Protein Ubiquitination	Vesicle-mediated Transport Mitotic Nuclear Division Cell Division Protein Localization Regulation Of Cellular Component Organization Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Transport Cell Cycle Mitotic Cell Cycle Process Negative Regulation Of Chromosome Segregation Protein Transport Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Establishment Of Protein Localization Mitotic Cell Cycle Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Protein Localization To Plasma Membrane Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of Organelle Organization Negative Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Negative Regulation Of Chromosome Organization Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Post-Golgi Vesicle-mediated Transport Cell Cycle Process Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Organelle Organization Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Negative Regulation Of Protein Catabolic Process Regulation Of Mitotic Nuclear Division Negative Regulation Of Hyaluronan Biosynthetic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Cellular Protein Localization Cellular Localization Small GTPase Mediated Signal Transduction Mitotic Cell Cycle Checkpoint Endocytosis Regulation Of Sequestering Of Zinc Ion Regulation Of Endocytosis Regulation Of Proteasomal Protein Catabolic Process Establishment Of Vesicle Localization Myeloid Cell Apoptotic Process Regulation Of Chromosome Organization Vesicle Localization
Tagcloud ?		aneuploidy apocrine arp2 beta1 biomarker box broad cytokinesis exploring forkhead foxm1 inside integrin luminal m1 microtubule mitosis mitotic notable partners pip polymerization prolactin proteomic rationale signature silencing talin tubulin	amd3100 bl bortezomib c57bl6 canine cathepsin cbcs cfu cfus ch counts cyclic cyclophosphamide dilution elastase gemm granulocyte granulopoiesis hermansky hps lin lsk mobilization myeloperoxidase neutropenia neutropenic pearl pudlak sca
Tagcloud (Difference) ?		aneuploidy apocrine arp2 beta1 biomarker box broad cytokinesis exploring forkhead foxm1 inside integrin luminal m1 microtubule mitosis mitotic notable partners pip polymerization prolactin proteomic rationale signature silencing talin tubulin	amd3100 bl bortezomib c57bl6 canine cathepsin cbcs cfu cfus ch counts cyclic cyclophosphamide dilution elastase gemm granulocyte granulopoiesis hermansky hps lin lsk mobilization myeloperoxidase neutropenia neutropenic pearl pudlak sca
Tagcloud (Intersection) ?