BUB1 and AP4B1

Number of citations of the paper that reports this interaction (PMID 12419313)
4

Data Source:
HPRD (two hybrid)

		BUB1	AP4B1
Gene Name		BUB1 mitotic checkpoint serine/threonine kinase	adaptor-related protein complex 4, beta 1 subunit
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Condensed Nuclear Chromosome, Centromeric Region Nucleoplasm Cytoplasm Cytosol Membrane	Trans-Golgi Network Coated Pit Clathrin Adaptor Complex
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Transporter Activity Protein Transporter Activity
	Biological Process	Mitotic Cell Cycle Protein Phosphorylation Apoptotic Process Chromosome Segregation Regulation Of Sister Chromatid Cohesion Mitotic Nuclear Division Mitotic Cell Cycle Checkpoint Mitotic Spindle Assembly Checkpoint Cell Proliferation Viral Process Cell Division Regulation Of Chromosome Segregation Spindle Assembly Checkpoint Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Intracellular Protein Transport Vesicle-mediated Transport
Pathways		Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase	Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS			Breast cancer ( 23535729) Obesity-related traits ( 23251661)
Protein-Protein Interactions		18 interactors: AP1B1 AP2B1 AP3B1 AP4B1 APC ARIH2 BUB1B BUB3 CASC5 CDC20 CDK1 CRK EIF4EBP1 HDAC1 PLK1 RAE1 RDH12 SVIL	5 interactors: AP4E1 AP4M1 BUB1 BUB1B ZNF576
Entrez ID		699	10717
HPRD ID		03907	06259
Ensembl ID		ENSG00000169679	ENSG00000134262
Uniprot IDs		B4DYG2 E9PC26 F5GXI5 O43683	B4DTG3 Q9Y6B7
PDB IDs		2LAH 3E7E 4A1G
Enriched GO Terms of Interacting Partners?		Spindle Assembly Checkpoint Spindle Checkpoint Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Mitotic Cell Cycle Mitotic Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Regulation Of Mitotic Sister Chromatid Separation Cell Cycle Checkpoint Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Mitotic Cell Cycle Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Proteasomal Protein Catabolic Process Mitotic Cell Cycle Checkpoint Mitotic Nuclear Division Negative Regulation Of Cellular Protein Catabolic Process Regulation Of Chromosome Segregation Negative Regulation Of Cell Division Regulation Of Ubiquitin-protein Transferase Activity Protein Localization To Chromosome Negative Regulation Of Chromosome Organization Regulation Of Cell Cycle Cell Cycle Metaphase/anaphase Transition Of Mitotic Cell Cycle Negative Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Cell Division Cell Cycle Process Negative Regulation Of Cell Cycle Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Division Negative Regulation Of Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Mitotic Nuclear Division Protein Localization To Kinetochore Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Localization To Chromosome, Centromeric Region Negative Regulation Of Mitotic Cell Cycle Phase Transition Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Cellular Protein Localization Protein Catabolic Process Regulation Of Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Chromosome Organization Regulation Of Protein Ubiquitination	Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Negative Regulation Of Chromosome Organization Negative Regulation Of Protein Catabolic Process Regulation Of Mitotic Nuclear Division Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Checkpoint Regulation Of Proteasomal Protein Catabolic Process Regulation Of Chromosome Organization Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition Cell Cycle Checkpoint Regulation Of Cell Division Cellular Protein Localization Mitotic Nuclear Division Metaphase/anaphase Transition Of Mitotic Cell Cycle Protein Localization To Kinetochore Negative Regulation Of Proteolysis Protein Localization To Chromosome, Centromeric Region Negative Regulation Of Protein Processing Regulation Of Protein Catabolic Process Regulation Of Protein Processing Regulation Of Mitotic Cell Cycle Cell Division Negative Regulation Of Cell Cycle Regulation Of Sister Chromatid Cohesion Golgi To Endosome Transport Regulation Of Cell Cycle Process Protein Localization Protein Localization To Chromosome Regulation Of Proteolysis Mitotic Cell Cycle Process Cell Proliferation Cellular Localization Mitotic Cell Cycle Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Tagcloud ?		aneuploidy apocrine arp2 beta1 biomarker box broad cytokinesis exploring forkhead foxm1 inside integrin luminal m1 microtubule mitosis mitotic notable partners pip polymerization prolactin proteomic rationale signature silencing talin tubulin
Tagcloud (Difference) ?		aneuploidy apocrine arp2 beta1 biomarker box broad cytokinesis exploring forkhead foxm1 inside integrin luminal m1 microtubule mitosis mitotic notable partners pip polymerization prolactin proteomic rationale signature silencing talin tubulin
Tagcloud (Intersection) ?