BID and C14orf1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		BID	C14orf1
Gene Name		BH3 interacting domain death agonist	chromosome 14 open reading frame 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Cytosol Membrane Integral Component Of Mitochondrial Membrane Extracellular Vesicular Exosome	Endoplasmic Reticulum Membrane Integral Component Of Membrane Transport Vesicle
	Molecular Function	Death Receptor Binding Protein Binding Ubiquitin Protein Ligase Binding	Molecular_function
	Biological Process	Release Of Cytochrome C From Mitochondria Protein Targeting To Mitochondrion Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Brain Development Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Apoptotic Mitochondrial Changes Response To Estradiol Positive Regulation Of Protein Oligomerization Positive Regulation Of Protein Homooligomerization Glial Cell Apoptotic Process Regulation Of Cell Proliferation Signal Transduction In Response To DNA Damage Positive Regulation Of Apoptotic Process Protein Homooligomerization Neuron Apoptotic Process Establishment Of Protein Localization To Membrane Positive Regulation Of Release Of Cytochrome C From Mitochondria Intrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process Mitochondrial Outer Membrane Permeabilization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Biological_process Sterol Biosynthetic Process
Pathways		Activation of BAD and translocation to mitochondria Activation, translocation and oligomerization of BAX Activation, myristolyation of BID and translocation to mitochondria Programmed Cell Death Activation of BH3-only proteins Activation and oligomerization of BAK protein BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members Intrinsic Pathway for Apoptosis
Drugs
Diseases
GWAS
Protein-Protein Interactions		36 interactors: AHCYL1 BAK1 BAX BCL2 BCL2A1 BCL2L1 BCL2L2 C14orf1 CAPN1 CAPN2 CASP1 CASP10 CASP2 CASP3 CASP8 CRMP1 CRNKL1 CSNK1A1 CSNK1E CSNK2A1 CSNK2A2 CSNK2B FBN3 GAPDH GBP2 GZMB MCL1 PLEKHM1 RBM48 REL RPA1 SETDB1 TLE1 TUBB2B YWHAB ZHX1	62 interactors: ALDH2 ANXA1 ANXA7 BAIAP2 BID BTBD2 CCDC106 CCL18 CDC42 CDK5RAP2 CELF3 CLN8 COX17 CRADD CREB1 CSTF2 DYNLL1 FAS FCGR2B FXR1 GADD45A GSK3B HMGB1 HNRNPH3 HNRNPUL1 HSPE1 HYLS1 KLHL20 LSM2 MAPK8IP2 MPHOSPH6 MRPL38 MRPS12 NAT9 NDUFA4L2 NR1H2 NSF PAFAH1B3 PCDHA4 PEX2 PFN1 PHYHIP POLE2 POLR2C POLR3F PPP1R8 PQBP1 RAB27A RPS6KA6 S100A8 SAT1 SEPHS1 SERPINB9 SNRPB SNRPG SULT1E1 TFG TK1 TSC22D1 TTR ZFP64 ZNF24
Entrez ID		637	11161
HPRD ID		03590	05201
Ensembl ID		ENSG00000015475
Uniprot IDs		A8ASI8 B2ZP79 B3KT21 P55957	Q6FII3 Q86TW5 Q9UKR5
PDB IDs		1ZY3 2BID 2KBW 2M5B 4BD2
Enriched GO Terms of Interacting Partners?		Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Intrinsic Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway Apoptotic Signaling Pathway Apoptotic Process Programmed Cell Death Cell Death Death Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Signal Transduction Regulation Of Cell Death Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Apoptotic Process Regulation Of Mitochondrion Organization Positive Regulation Of Mitochondrion Organization Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Release Of Cytochrome C From Mitochondria Positive Regulation Of Cell Death Regulation Of Signal Transduction Apoptotic Mitochondrial Changes Regulation Of Mitochondrial Membrane Potential Protein Processing Regulation Of Signaling Cell Surface Receptor Signaling Pathway Cellular Response To Stimulus Negative Regulation Of Anoikis Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Response To DNA Damage Stimulus Neuron Apoptotic Process Regulation Of Anoikis Signal Transduction Regulation Of Cysteine-type Endopeptidase Activity Response To Stress Neuron Death Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Negative Regulation Of Cell Death Signaling Regulation Of Intrinsic Apoptotic Signaling Pathway Intracellular Signal Transduction Cell Communication Response To Stimulus Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Neuron Death Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Mitochondrial Membrane Permeability Activation Of Cysteine-type Endopeptidase Activity Regulation Of Membrane Permeability	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death MRNA Processing Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process MRNA Metabolic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Nervous System Development Regulation Of Cysteine-type Endopeptidase Activity RNA Processing Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Endopeptidase Activity Regulation Of Apoptotic Process Positive Regulation Of Peptidase Activity Cellular Metabolic Process Regulation Of Cell Death Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Proteolysis Activation Of Cysteine-type Endopeptidase Activity Nucleobase-containing Compound Metabolic Process Anatomical Structure Development Response To Stress Regulation Of Catalytic Activity Zymogen Activation Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Apoptotic Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Developmental Process Nitrogen Compound Metabolic Process Response To External Stimulus Apoptotic Process Metabolic Process Programmed Cell Death Regulation Of Metabolic Process Regulation Of Cellular Component Organization Cell Death Death Cellular Response To Mechanical Stimulus DNA-templated Transcription, Termination System Development Regulation Of Endopeptidase Activity Immune Response Positive Regulation Of Catalytic Activity Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Tagcloud ?		3n burns catheter caustic cd ceb ceftazidime contents corticosteroids cp created decreasing dexamethasone ensues esophageal esophagograms grouped histologic hydroxide hydroxyproline im indwelling infused massive pentoxifylline scatritial stricture tid wistar
Tagcloud (Difference) ?		3n burns catheter caustic cd ceb ceftazidime contents corticosteroids cp created decreasing dexamethasone ensues esophageal esophagograms grouped histologic hydroxide hydroxyproline im indwelling infused massive pentoxifylline scatritial stricture tid wistar
Tagcloud (Intersection) ?