C14orf1 and RPS6KA6

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		C14orf1	RPS6KA6
Gene Name		chromosome 14 open reading frame 1	ribosomal protein S6 kinase, 90kDa, polypeptide 6
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Transport Vesicle	Nucleus Nucleoplasm Nucleolus Mitochondrion Cytosol
	Molecular Function	Molecular_function	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity ATP Binding
	Biological Process	Biological_process Sterol Biosynthetic Process	Protein Phosphorylation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Signal Transduction Synaptic Transmission Axon Guidance Central Nervous System Development Negative Regulation Of Embryonic Development Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Mesoderm Development
Pathways			Axon guidance RSK activation Activation of NMDA receptor upon glutamate binding and postsynaptic events L1CAM interactions Recycling pathway of L1 CREB phosphorylation through the activation of Ras Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Transmission across Chemical Synapses Post NMDA receptor activation events
Drugs
Diseases
GWAS
Protein-Protein Interactions		62 interactors: ALDH2 ANXA1 ANXA7 BAIAP2 BID BTBD2 CCDC106 CCL18 CDC42 CDK5RAP2 CELF3 CLN8 COX17 CRADD CREB1 CSTF2 DYNLL1 FAS FCGR2B FXR1 GADD45A GSK3B HMGB1 HNRNPH3 HNRNPUL1 HSPE1 HYLS1 KLHL20 LSM2 MAPK8IP2 MPHOSPH6 MRPL38 MRPS12 NAT9 NDUFA4L2 NR1H2 NSF PAFAH1B3 PCDHA4 PEX2 PFN1 PHYHIP POLE2 POLR2C POLR3F PPP1R8 PQBP1 RAB27A RPS6KA6 S100A8 SAT1 SEPHS1 SERPINB9 SNRPB SNRPG SULT1E1 TFG TK1 TSC22D1 TTR ZFP64 ZNF24	28 interactors: ADIRF APP C14orf1 CEBPZ CENPB CLEC3B DHX34 DNAJC13 DNMT1 FBN3 FZD5 LMO4 MAPK3 MASP1 MED24 MICAL1 MPP1 NR4A1 RBPJ RPLP1 RXRA SAP30BP SPTBN4 SYNE4 UBE2I UFM1 ZNF227 ZNF746
Entrez ID		11161	27330
HPRD ID		05201	02250
Ensembl ID
Uniprot IDs		Q6FII3 Q86TW5 Q9UKR5	Q9UK32
PDB IDs
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death MRNA Processing Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process MRNA Metabolic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Nervous System Development Regulation Of Cysteine-type Endopeptidase Activity RNA Processing Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Endopeptidase Activity Regulation Of Apoptotic Process Positive Regulation Of Peptidase Activity Cellular Metabolic Process Regulation Of Cell Death Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Proteolysis Activation Of Cysteine-type Endopeptidase Activity Nucleobase-containing Compound Metabolic Process Anatomical Structure Development Response To Stress Regulation Of Catalytic Activity Zymogen Activation Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Apoptotic Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Developmental Process Nitrogen Compound Metabolic Process Response To External Stimulus Apoptotic Process Metabolic Process Programmed Cell Death Regulation Of Metabolic Process Regulation Of Cellular Component Organization Cell Death Death Cellular Response To Mechanical Stimulus DNA-templated Transcription, Termination System Development Regulation Of Endopeptidase Activity Immune Response Positive Regulation Of Catalytic Activity Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway	Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Gene Expression Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Positive Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process DNA-templated Transcription, Initiation Positive Regulation Of Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Intracellular Receptor Signaling Pathway Regulation Of Protein Metabolic Process Regulation Of Protein Processing Regulation Of Early Endosome To Late Endosome Transport Cell Differentiation Biosynthetic Process Cardiac Ventricle Development Negative Regulation Of Cellular Metabolic Process Labyrinthine Layer Blood Vessel Development Sterol Metabolic Process Tissue Development Cardiac Chamber Development Neuron Maturation Regulation Of Cell Fate Commitment Apoptotic Process Cell Maturation Negative Regulation Of Protein Processing Regulation Of Cellular Process Tissue Morphogenesis Programmed Cell Death Placenta Blood Vessel Development
Tagcloud ?			anchorage anticipated attribution azacytidine cdna chemoresponse clines codons deleted demethylation depended duplet encompass exclude exon immunoblots indolocarbazole isoforms nt nucleotides penultimate rsk4 situation sparse splice starvation suppressive triplet uncharacterized
Tagcloud (Difference) ?			anchorage anticipated attribution azacytidine cdna chemoresponse clines codons deleted demethylation depended duplet encompass exclude exon immunoblots indolocarbazole isoforms nt nucleotides penultimate rsk4 situation sparse splice starvation suppressive triplet uncharacterized
Tagcloud (Intersection) ?