RAD23B and MPG

Number of citations of the paper that reports this interaction (PMID 10854423)
26

Data Source:
HPRD (in vitro)

		RAD23B	MPG
Gene Name		RAD23 homolog B (S. cerevisiae)	N-methylpurine-DNA glycosylase
Image
Gene Ontology Annotations	Cellular Component	Proteasome Complex Nucleus Nucleoplasm Cytoplasm XPC Complex	Nucleoplasm Mitochondrial Nucleoid
	Molecular Function	Damaged DNA Binding Single-stranded DNA Binding Protein Binding Polyubiquitin Binding	Damaged DNA Binding Alkylbase DNA N-glycosylase Activity Protein Binding DNA-3-methyladenine Glycosylase Activity DNA-7-methylguanine Glycosylase Activity DNA-7-methyladenine Glycosylase Activity DNA-3-methylguanine Glycosylase Activity
	Biological Process	Nucleotide-excision Repair, DNA Damage Recognition Nucleotide-excision Repair, DNA Damage Removal DNA Repair Nucleotide-excision Repair Spermatogenesis Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	DNA Repair Base-excision Repair Base-excision Repair, AP Site Formation DNA Dealkylation Involved In DNA Repair Depurination
Pathways		Nucleotide Excision Repair Global Genomic NER (GG-NER) Formation of incision complex in GG-NER DNA Damage Recognition in GG-NER Dual incision reaction in GG-NER	Depurination Base Excision Repair Resolution of AP sites via the multiple-nucleotide patch replacement pathway Base-Excision Repair, AP Site Formation Removal of DNA patch containing abasic residue Resolution of AP sites via the single-nucleotide replacement pathway Base-free sugar-phosphate removal via the single-nucleotide replacement pathway Displacement of DNA glycosylase by APE1 Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine Resolution of Abasic Sites (AP sites)
Drugs
Diseases
GWAS		Body mass index ( 20966902) Breast cancer ( 21263130) Prostate cancer ( 23023329)	Red blood cell traits ( 23446634)
Protein-Protein Interactions		20 interactors: ADRM1 ATXN3 CALM1 DBI DEAF1 HMGB1 MLH1 MPG NGLY1 PAX3 PNMA5 PSMD4 PUF60 RPA1 TDG UBA2 UBB UBE3A XPC ZFAND5	9 interactors: APP EP300 ESR1 HSD17B14 RAD23A RAD23B RXRA TERF2IP THRB
Entrez ID		5887	4350
HPRD ID		06772	06766
Ensembl ID		ENSG00000119318	ENSG00000103152
Uniprot IDs		B7Z4W4 P54727	P29372 Q1W6H1
PDB IDs		1P1A 1PVE 1UEL	1BNK 1EWN 1F4R 1F6O 3QI5 3UBY
Enriched GO Terms of Interacting Partners?		Cellular Macromolecule Catabolic Process Catabolic Process Cellular Response To DNA Damage Stimulus DNA Repair DNA Catabolic Process Base-excision Repair DNA Metabolic Process Nitrogen Compound Metabolic Process Aromatic Compound Catabolic Process Cellular Response To Stress Response To Stress Cellular Nitrogen Compound Metabolic Process Protein Catabolic Process Mismatch Repair Cellular Metabolic Process Base-excision Repair, AP Site Formation Modification-dependent Protein Catabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Nucleotide-excision Repair Mitotic DNA Damage Checkpoint Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Mitotic DNA Integrity Checkpoint Multicellular Organismal Development Positive Regulation Of Proteolysis Heterocycle Metabolic Process Deoxyribose Phosphate Catabolic Process Cellular Aromatic Compound Metabolic Process Apoptotic Process Nucleotide-excision Repair, DNA Damage Removal Anatomical Structure Development Programmed Cell Death System Development Cell Death Death Negative Regulation Of Cellular Metabolic Process Regulation Of Proteolysis Response To Abiotic Stimulus Deoxyribonucleotide Catabolic Process DNA Damage Checkpoint Nervous System Development G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Checkpoint Protein Polyubiquitination Developmental Process Behavioral Fear Response Fear Response Transcription From RNA Polymerase II Promoter Regulation Of Cell Cycle Process	Intracellular Receptor Signaling Pathway Steroid Metabolic Process Regulation Of Branching Involved In Prostate Gland Morphogenesis Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Reproduction Response To Steroid Hormone Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Cellular Response To Steroid Hormone Stimulus Mating Behavior Reproductive Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Nitrogen Compound Metabolic Process DNA-templated Transcription, Initiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Multicellular Organismal Reproductive Process Mating Multicellular Organism Reproduction Response To Lipid Cellular Response To DNA Damage Stimulus Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Organic Cyclic Compound Cellular Response To Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Response To Hormone Regulation Of Morphogenesis Of A Branching Structure Prostate Gland Development Positive Regulation Of Viral Process Organ Morphogenesis RNA Metabolic Process Cellular Response To Organic Cyclic Compound Chromosome Organization Regulation Of Cellular Protein Metabolic Process Histone H2B Acetylation Negative Regulation Of DNA Recombination At Telomere Maternal Process Involved In Female Pregnancy Cellular Response To Lipid Epithelium Development Negative Regulation Of Cellular Metabolic Process Gene Expression Posttranscriptional Regulation Of Gene Expression
Tagcloud ?		a3 adoptive bioinformatic blunting dige diploid disulfide excision galactosidase hnrnpa3 hnrnpq imr90 isomerase lesser mir mirrored pdia3 permanent perturbation proteome ribonucleoprotein senescence senescent slowed synaptotagmin syncrip untranslated utrs	adherens arg1 cadherin cadherins clustered coculture coculturing coimmunoprecipitation csi desmocollin desmoglein desmoplakin desmosomal desmosomes dsc dsc1 dsc1a dsg dsg2 fibrosarcoma ht intercellular junctions lysates plakoglobin portion repeats tagged thr170
Tagcloud (Difference) ?		a3 adoptive bioinformatic blunting dige diploid disulfide excision galactosidase hnrnpa3 hnrnpq imr90 isomerase lesser mir mirrored pdia3 permanent perturbation proteome ribonucleoprotein senescence senescent slowed synaptotagmin syncrip untranslated utrs	adherens arg1 cadherin cadherins clustered coculture coculturing coimmunoprecipitation csi desmocollin desmoglein desmoplakin desmosomal desmosomes dsc dsc1 dsc1a dsg dsg2 fibrosarcoma ht intercellular junctions lysates plakoglobin portion repeats tagged thr170
Tagcloud (Intersection) ?