QARS and TSC22D1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		QARS	TSC22D1
Gene Name		glutaminyl-tRNA synthetase	TSC22 domain family, member 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrial Matrix Cytosol	Nucleus Cytoplasm
	Molecular Function	Glutamine-tRNA Ligase Activity Protein Binding ATP Binding	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Glutaminyl-tRNA Aminoacylation Brain Development Gene Expression	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Proliferation Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process
Pathways		Cytosolic tRNA aminoacylation tRNA Aminoacylation Mitochondrial tRNA aminoacylation
Drugs
Diseases
GWAS			Antineutrophil cytoplasmic antibody-associated vasculitis ( 22808956)
Protein-Protein Interactions		37 interactors: AES ANXA7 APP ASL CDK4 CDKN1A CLTC CPNE3 DPPA4 DTX2 DUSP11 FAM118B GADD45A GSK3B H2AFX IRF1 KCNE3 KLC3 LAMTOR3 LZTS2 MAP3K5 PIK3R3 PIN1 PRRC2A RARS RNF11 SMAD9 SMN1 STK3 TCF12 TK1 TRAF2 TRAF4 TRIP13 TSC22D1 TTR VPS37B	49 interactors: A2M APLP1 ASAH1 C14orf1 C9orf9 CACNA1A CARHSP1 CCDC90B CHD3 CORO2B CRMP1 DDAH2 DNMT3B EED FAF1 FAM20C FBN3 GNB2 GNB5 HMGXB4 KMT2B KMT2C LRIF1 MAP3K12 MCM3AP NCOA5 OTUB1 PDHB PRKCI PTN QARS RGS1 RPL5 SETDB1 SP110 SPRED1 TAF5L TGFBR1 TLE1 TP53 TSC22D4 UBE2D1 UNC119 VIM WDR73 WDYHV1 WIZ WNK1 ZC3HC1
Entrez ID		5859	8848
HPRD ID		07223	07414
Ensembl ID		ENSG00000172053
Uniprot IDs		B4DWJ2 B7Z840 P47897	A8K3Y6 Q15714
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Binding Regulation Of Kinase Activity Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Cellular Metabolic Process Regulation Of Protein Kinase Activity Positive Regulation Of Protein Metabolic Process Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Phosphorylation Positive Regulation Of Apoptotic Process Regulation Of Protein Phosphorylation Regulation Of Binding Response To Abiotic Stimulus Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Binding Regulation Of JNK Cascade Response To Inorganic Substance Regulation Of Phosphorus Metabolic Process Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Phosphorylation Apoptotic Process Programmed Cell Death Positive Regulation Of Transferase Activity Cell Cycle Process Metabolic Process Cell Death Death Cell Cycle Cellular Protein Modification Process Regulation Of MAPK Cascade Positive Regulation Of Phosphorylation Regulation Of Apoptotic Process Positive Regulation Of Binding Cellular Process Positive Regulation Of Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Catalytic Activity Regulation Of Cell Death Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Catalytic Activity Positive Regulation Of Protein Homodimerization Activity Regulation Of Metabolic Process Response To Stimulus Innate Immune Response	Regulation Of Metabolic Process Chromatin Organization Chromatin Modification Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cellular Process Regulation Of Cellular Protein Metabolic Process Chromosome Organization Regulation Of Chromosome Organization Regulation Of Histone Modification Regulation Of Protein Metabolic Process Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Nitrogen Compound Metabolic Process RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Histone Methylation Histone Modification Gene Expression Cellular Nitrogen Compound Metabolic Process Peptidyl-threonine Phosphorylation RNA Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Signal Transduction Heterocycle Metabolic Process Regulation Of Histone Methylation Cellular Aromatic Compound Metabolic Process Regulation Of Cellular Component Organization Signal Transduction Transcription, DNA-templated Cellular Response To Stimulus Negative Regulation Of Signaling Regulation Of Phosphorus Metabolic Process Response To Stimulus Protein Methylation Positive Regulation Of Histone Modification Regulation Of Transcription, DNA-templated Organelle Organization Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Signaling Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Cell Communication Histone Lysine Methylation Negative Regulation Of Chromosome Organization Negative Regulation Of Cellular Protein Metabolic Process
Tagcloud ?		aars acylating aminoacyl aminoars aminoarss bodies canonical dorsal drg functions ganglia glutaminyl horn injured kars lysyl nerve pharmaceutical possibility powerful primers root satellite sensory spinal synthetase synthetases trna typical	beadchip capn13 cards cic collect conjunctival cxcl6 cytology drb5 dry entire eye ht illumina impression investigates lysozyme mini optimally optimization psca qiagen qrt qualifying rneasy severities steps taqman transcriptome
Tagcloud (Difference) ?		aars acylating aminoacyl aminoars aminoarss bodies canonical dorsal drg functions ganglia glutaminyl horn injured kars lysyl nerve pharmaceutical possibility powerful primers root satellite sensory spinal synthetase synthetases trna typical	beadchip capn13 cards cic collect conjunctival cxcl6 cytology drb5 dry entire eye ht illumina impression investigates lysozyme mini optimally optimization psca qiagen qrt qualifying rneasy severities steps taqman transcriptome
Tagcloud (Intersection) ?