QARS and DUSP11

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		QARS	DUSP11
Gene Name		glutaminyl-tRNA synthetase	dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrial Matrix Cytosol	Nucleus Nuclear Speck
	Molecular Function	Glutamine-tRNA Ligase Activity Protein Binding ATP Binding	RNA Binding Polynucleotide 5'-phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Tyrosine/serine/threonine Phosphatase Activity Phosphatase Activity Poly(A) RNA Binding Nucleotide Phosphatase Activity, Acting On Free Nucleotides
	Biological Process	TRNA Aminoacylation For Protein Translation Glutaminyl-tRNA Aminoacylation Brain Development Gene Expression	RNA Processing RNA Metabolic Process Peptidyl-tyrosine Dephosphorylation Polynucleotide 5' Dephosphorylation
Pathways		Cytosolic tRNA aminoacylation tRNA Aminoacylation Mitochondrial tRNA aminoacylation
Drugs
Diseases
GWAS			Creatinine levels ( 20383145) Metabolite levels ( 21931564)
Protein-Protein Interactions		37 interactors: AES ANXA7 APP ASL CDK4 CDKN1A CLTC CPNE3 DPPA4 DTX2 DUSP11 FAM118B GADD45A GSK3B H2AFX IRF1 KCNE3 KLC3 LAMTOR3 LZTS2 MAP3K5 PIK3R3 PIN1 PRRC2A RARS RNF11 SMAD9 SMN1 STK3 TCF12 TK1 TRAF2 TRAF4 TRIP13 TSC22D1 TTR VPS37B	3 interactors: QARS SRSF7 SRSF9
Entrez ID		5859	8446
HPRD ID		07223	04368
Ensembl ID		ENSG00000172053	ENSG00000144048
Uniprot IDs		B4DWJ2 B7Z840 P47897	C9JYA6 O75319
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Binding Regulation Of Kinase Activity Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Cellular Metabolic Process Regulation Of Protein Kinase Activity Positive Regulation Of Protein Metabolic Process Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Phosphorylation Positive Regulation Of Apoptotic Process Regulation Of Protein Phosphorylation Regulation Of Binding Response To Abiotic Stimulus Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Binding Regulation Of JNK Cascade Response To Inorganic Substance Regulation Of Phosphorus Metabolic Process Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Phosphorylation Apoptotic Process Programmed Cell Death Positive Regulation Of Transferase Activity Cell Cycle Process Metabolic Process Cell Death Death Cell Cycle Cellular Protein Modification Process Regulation Of MAPK Cascade Positive Regulation Of Phosphorylation Regulation Of Apoptotic Process Positive Regulation Of Binding Cellular Process Positive Regulation Of Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Catalytic Activity Regulation Of Cell Death Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Catalytic Activity Positive Regulation Of Protein Homodimerization Activity Regulation Of Metabolic Process Response To Stimulus Innate Immune Response	Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Termination Of RNA Polymerase II Transcription Regulation Of MRNA Splicing, Via Spliceosome MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus MRNA 3'-end Processing Regulation Of MRNA Processing Regulation Of RNA Splicing RNA 3'-end Processing Nuclear Export MRNA Transport RNA Transport RNA Localization Glutaminyl-tRNA Aminoacylation Negative Regulation Of Gene Expression Prolyl-tRNA Aminoacylation MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleocytoplasmic Transport Nuclear Transport Glutamyl-tRNA Aminoacylation RNA Splicing Negative Regulation Of Cellular Metabolic Process MRNA Processing MRNA Metabolic Process RNA Processing Cytoplasmic Transport RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter MRNA Splice Site Selection Nucleobase-containing Compound Metabolic Process Spliceosomal Complex Assembly Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Translation Intracellular Transport Nitrogen Compound Metabolic Process TRNA Aminoacylation For Protein Translation TRNA Aminoacylation Cellular Component Assembly Cellular Response To Interferon-gamma Establishment Of Localization In Cell
Tagcloud ?		aars acylating aminoacyl aminoars aminoarss bodies canonical dorsal drg functions ganglia glutaminyl horn injured kars lysyl nerve pharmaceutical possibility powerful primers root satellite sensory spinal synthetase synthetases trna typical
Tagcloud (Difference) ?		aars acylating aminoacyl aminoars aminoarss bodies canonical dorsal drg functions ganglia glutaminyl horn injured kars lysyl nerve pharmaceutical possibility powerful primers root satellite sensory spinal synthetase synthetases trna typical
Tagcloud (Intersection) ?