PNRC2 and ZBTB48

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		PNRC2	ZBTB48
Gene Name		proline-rich nuclear receptor coactivator 2	zinc finger and BTB domain containing 48
Image
Gene Ontology Annotations	Cellular Component	Cytoplasmic MRNA Processing Body Nucleus	Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Metal Ion Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Transcription, DNA-templated Regulation Of Transcription, DNA-templated Deadenylation-independent Decapping Of Nuclear-transcribed MRNA	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		20 interactors: AR DCP1A ESR1 ESR2 ESRRA ESRRG GLOD4 HNF4A HNF4G NR5A1 NR5A2 RARA RARG RORA RORB SF1 SPAG9 XRCC6 ZBTB16 ZBTB48	17 interactors: C11orf58 C7orf34 CDK2AP2 CDKN1A DVL3 EP300 GPATCH2L ILK KRTAP10-5 NME7 NUDT21 PNRC2 RGS2 TNFRSF14 UPF2 ZBTB7A ZBTB8A
Entrez ID		55629	3104
HPRD ID		17871	01316
Ensembl ID		ENSG00000189266	ENSG00000204859
Uniprot IDs		Q9NPJ4	A8K291 B2R702 P10074
PDB IDs		4B6H	3B84
Enriched GO Terms of Interacting Partners?		Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Cellular Response To Steroid Hormone Stimulus Transcription Initiation From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway DNA-templated Transcription, Initiation Cellular Response To Organic Cyclic Compound Cellular Response To Lipid Response To Steroid Hormone Cellular Response To Hormone Stimulus Transcription From RNA Polymerase II Promoter Response To Lipid Response To Organic Cyclic Compound Response To Hormone Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process RNA Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Gene Expression Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Response To Organic Substance Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Organ Development Response To Organic Substance Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process System Development Developmental Process Involved In Reproduction Prostate Gland Development Sex Differentiation Multicellular Organismal Development Anatomical Structure Development Regulation Of Metabolic Process	Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Regulation Of Protein Phosphorylation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Regulation Of MAP Kinase Activity Regulation Of Protein Kinase Activity Negative Regulation Of Transferase Activity Regulation Of Protein Metabolic Process Cellular Response To Heat Histone H2B Acetylation Negative Regulation Of Protein Phosphorylation Regulation Of Kinase Activity Cell Aging Organ Regeneration Regulation Of Phosphorus Metabolic Process Positive Regulation Of Phosphorylation Positive Regulation Of Protein Modification Process Deadenylation-independent Decapping Of Nuclear-transcribed MRNA Negative Regulation Of Phosphorylation Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process N-terminal Peptidyl-lysine Acetylation Response To Heat Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Kinase Activity G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Kinase Activity Positive Regulation Of Cytokine Secretion Involved In Immune Response Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Tubulin Deacetylation Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway Intestinal Epithelial Cell Maturation Non-canonical Wnt Signaling Pathway Via JNK Cascade MRNA Metabolic Process Cell Cycle Arrest Nuclear-transcribed MRNA Catabolic Process Organ Development Positive Regulation Of Transferase Activity Positive Regulation Of Wnt Signaling Pathway Developmental Process Regulation Of Adrenergic Receptor Signaling Pathway
Tagcloud ?		2d af alternatives biologically circular coactivators cognate competitive confirms constitutes coregulator coregulators dichroism ecd eralpha eralpha17p exception exhaustive governing grb2 issued motifs polyproline ppii pxxp sh3 spectroscopy transductions
Tagcloud (Difference) ?		2d af alternatives biologically circular coactivators cognate competitive confirms constitutes coregulator coregulators dichroism ecd eralpha eralpha17p exception exhaustive governing grb2 issued motifs polyproline ppii pxxp sh3 spectroscopy transductions
Tagcloud (Intersection) ?