NOV and S100A4

Number of citations of the paper that reports this interaction (PMID 12147716)
19

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		NOV	S100A4
Gene Name		nephroblastoma overexpressed	S100 calcium binding protein A4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Proteinaceous Extracellular Matrix Axon Dendrite Neuronal Cell Body Intracellular Membrane-bounded Organelle	Extracellular Space Nucleus Neuron Projection Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Integrin Binding Insulin-like Growth Factor Binding Growth Factor Activity Heparin Binding	Actin Binding Calcium Ion Binding Protein Binding Identical Protein Binding Poly(A) RNA Binding Calcium-dependent Protein Binding RAGE Receptor Binding
	Biological Process	Regulation Of Cell Growth Cell Adhesion Signal Transduction Cell-cell Signaling Regulation Of Gene Expression Negative Regulation Of Cell Death	Epithelial To Mesenchymal Transition Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways
Drugs		Insulin Regular Insulin, porcine
Diseases
GWAS		Blood pressure ( 21909110) Hypertension ( 21626137)
Protein-Protein Interactions		14 interactors: ADSL CDKN1A CTGF DLL1 FBLN1 FN1 GJA1 IGF1 IGF2 INS ITGAV NOTCH1 POLR2L S100A4	22 interactors: ACTA1 ANXA2 BAG6 MDM2 METAP2 MYH10 MYH2 MYH4 MYH9 NOV PPFIBP1 S100A1 S100B S100P SEPT2 SEPT6 SEPT7 SMAD3 TP53 TPM2 TPM3 UNC119
Entrez ID		4856	6275
HPRD ID		01291	15914
Ensembl ID		ENSG00000136999	ENSG00000196154
Uniprot IDs		P48745	P26447
PDB IDs			1M31 2LNK 2Q91 3C1V 3CGA 3KO0 3M0W 3ZWH 4ETO 4HSZ
Enriched GO Terms of Interacting Partners?		Response To Wounding Wound Healing Regulation Of Growth Regulation Of Cell Differentiation Positive Regulation Of Glycogen Biosynthetic Process Developmental Process Tissue Development Positive Regulation Of Protein Metabolic Process Cell Development Cell Differentiation Positive Regulation Of Cell Cycle Process Positive Regulation Of Metabolic Process Positive Regulation Of Signal Transduction Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cell Proliferation Regulation Of Cellular Component Organization Cardiovascular System Development Multicellular Organismal Development Vasculature Development Anatomical Structure Development Positive Regulation Of Cell Cycle Regulation Of Cell Proliferation Regulation Of Protein Metabolic Process Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Glucose Metabolic Process System Development Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Glycogen Metabolic Process Anatomical Structure Morphogenesis Digestive System Development Tube Development Positive Regulation Of Mitotic Nuclear Division Response To Stress Compartment Pattern Specification Blood Vessel Morphogenesis Tissue Regeneration Response To Organonitrogen Compound Regulation Of Signal Transduction Positive Regulation Of Cell Differentiation Heart Looping Response To Peptide Regulation Of Cell Cycle Process Enzyme Linked Receptor Protein Signaling Pathway Determination Of Heart Left/right Asymmetry Secretion By Cell Blood Vessel Development Embryonic Heart Tube Morphogenesis Organ Development	Actin Filament-based Movement Actin-myosin Filament Sliding Muscle Filament Sliding Actin-mediated Cell Contraction Cell Cycle Process Cytokinesis Cell Cycle Actin Filament-based Process Muscle Contraction Cell Division Movement Of Cell Or Subcellular Component Muscle System Process Regulation Of Cell Shape Plasma Membrane Repair Response To External Stimulus Anatomical Structure Morphogenesis Cellular Component Assembly Anatomical Structure Formation Involved In Morphogenesis Mitotic Cell Cycle Process Regulation Of Cellular Component Organization Response To Abiotic Stimulus Mitotic Cell Cycle Regulation Of Cell Morphogenesis Cellular Response To Light Stimulus Cell Projection Morphogenesis Membrane Organization Cell Part Morphogenesis Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cell Development Response To Hypoxia Cellular Response To Oxygen Levels Actomyosin Structure Organization Signal Transduction By P53 Class Mediator Wound Healing Response To Light Stimulus Response To Stimulus Regulation Of Protein Stability Cellular Response To Radiation Cell Morphogenesis Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Response To Wounding Cell Differentiation Anatomical Structure Development Immune System Process Cellular Response To Stimulus System Development Cell Projection Organization Positive Regulation Of Transport Cell Adhesion
Tagcloud ?		autologous avian chicken cloned conserved element elements elevated encodes homolog igfii interrelated inversely kidney might nephroblastomas novh oncogene overexpressed predominantly proto putative relative represent sequenced stromal tumors wilms wt1	aldh1 anatomically area areas biomarkers cadherin cd44 central detailed egfr expressions fgfr1 heterogeneous immunohistochemical lymph metastatic molecules node nodes peripheral precise prediction recurrence relationships shorter sox2 squamous staining vegfr2
Tagcloud (Difference) ?		autologous avian chicken cloned conserved element elements elevated encodes homolog igfii interrelated inversely kidney might nephroblastomas novh oncogene overexpressed predominantly proto putative relative represent sequenced stromal tumors wilms wt1	aldh1 anatomically area areas biomarkers cadherin cd44 central detailed egfr expressions fgfr1 heterogeneous immunohistochemical lymph metastatic molecules node nodes peripheral precise prediction recurrence relationships shorter sox2 squamous staining vegfr2
Tagcloud (Intersection) ?