NFE2L1 and JUNB

Number of citations of the paper that reports this interaction (PMID 9872330)
77

Data Source:
HPRD (in vitro)

		NFE2L1	JUNB
Gene Name		nuclear factor, erythroid 2-like 1	jun B proto-oncogene
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Membrane Integral Component Of Membrane	Chromatin Nucleoplasm
	Molecular Function	RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Transcription Cofactor Activity	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA Binding Double-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding
	Biological Process	Transcription From RNA Polymerase II Promoter Heme Biosynthetic Process Inflammatory Response Anatomical Structure Morphogenesis Erythrocyte Differentiation Cellular Response To Oxidative Stress Positive Regulation Of Transcription From RNA Polymerase II Promoter	Vasculogenesis Osteoblast Differentiation Trophectodermal Cell Differentiation Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transforming Growth Factor Beta Receptor Signaling Pathway Response To Light Stimulus Response To Mechanical Stimulus Gene Expression Osteoclast Differentiation Response To Progesterone Cellular Response To Hormone Stimulus Osteoblast Proliferation Response To Cytokine Response To Drug Response To Peptide Hormone Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Decidualization Response To Corticosterone Response To CAMP Regulation Of Cell Cycle Embryonic Process Involved In Female Pregnancy Labyrinthine Layer Blood Vessel Development Cellular Response To Calcium Ion Negative Regulation Of Nucleic Acid-templated Transcription
Pathways			Loss of Function of TGFBR2 in Cancer TGFBR2 MSI Frameshift Mutants in Cancer SMAD2/3 Phosphorylation Motif Mutants in Cancer Loss of Function of SMAD2/3 in Cancer TGFBR2 Kinase Domain Mutants in Cancer Loss of Function of SMAD4 in Cancer SMAD2/3 MH2 Domain Mutants in Cancer TGFBR1 KD Mutants in Cancer TGFBR1 LBD Mutants in Cancer SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer Loss of Function of TGFBR1 in Cancer Generic Transcription Pathway Signaling by TGF-beta Receptor Complex Signaling by TGF-beta Receptor Complex in Cancer SMAD4 MH2 Domain Mutants in Cancer
Drugs
Diseases
GWAS		Epilepsy (generalized) ( 22949513)
Protein-Protein Interactions		14 interactors: ATF4 BACH2 CAPN1 CD6 CREBZF GSK3B HCFC1 JUN JUNB JUND MAFF MAFG MAFK NFE2L3	37 interactors: APLP2 ATF3 ATF4 BATF BATF2 BATF3 BCL6 BDNF BRCA1 C19orf68 DDIT3 EP300 ESR1 FOS FOSB FOSL1 FOSL2 HOXA7 JDP2 MAP2 MAPK14 MAPK6 MAPK8 MAPK9 NEU1 NFE2L1 NINL PKIA SAT1 SET SMAD3 SMAD4 SMURF1 TCERG1 TDG USP24 ZNF595
Entrez ID		4779	3726
HPRD ID		01223	01303
Ensembl ID		ENSG00000082641	ENSG00000171223
Uniprot IDs		B4DYE1 F5H1B7 J3QKY3 J9JIE5 Q14494 Q8NF22	P17275 Q5U079
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Circadian Rhythm Cellular Response To Calcium Ion Negative Regulation Of Biosynthetic Process Biosynthetic Process Response To Mechanical Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Rhythmic Process Negative Regulation Of RNA Biosynthetic Process Response To Metal Ion Response To Calcium Ion Regulation Of Metabolic Process Cellular Response To Metal Ion Positive Regulation Of Transcription, DNA-templated Regulation Of Epithelial Cell Differentiation Cellular Response To Inorganic Substance Negative Regulation Of Cellular Metabolic Process Response To Endoplasmic Reticulum Stress Positive Regulation Of Macromolecule Biosynthetic Process Response To Inorganic Substance Positive Regulation Of Gene Expression Cellular Metabolic Process Regulation Of Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Epidermal Cell Differentiation Response To External Stimulus Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Response To Wounding Positive Regulation Of Neuron Apoptotic Process	Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Metabolic Process Biosynthetic Process RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Cellular Response To Organic Substance Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Protein Metabolic Process Cellular Metabolic Process Regulation Of Protein Metabolic Process Response To Organic Substance Positive Regulation Of Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Gene Expression Response To External Stimulus Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Lipid Response To Mechanical Stimulus Positive Regulation Of Transcription, DNA-templated Anatomical Structure Development Response To Abiotic Stimulus Developmental Process Response To Corticosterone Response To Biotic Stimulus Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Stress Response To Mineralocorticoid Positive Regulation Of Cellular Biosynthetic Process
Tagcloud ?		11de 2e4 2g 7d1 7f1 amino basic chromosome cnc deduced drosophila embryo homologue identity isolated leucine library maps murine p45 seen sequence shows similar similarity subunit zipper	accumulated amplified clones delay differentiate differentiative ectopic epo erythroid erythropoietin evaluating g418 grow heavy introduced lg modifies modify neither plasmacytoma proliferated proliferative providing responsive retrovirally stat5 tepc transduced varied
Tagcloud (Difference) ?		11de 2e4 2g 7d1 7f1 amino basic chromosome cnc deduced drosophila embryo homologue identity isolated leucine library maps murine p45 seen sequence shows similar similarity subunit zipper	accumulated amplified clones delay differentiate differentiative ectopic epo erythroid erythropoietin evaluating g418 grow heavy introduced lg modifies modify neither plasmacytoma proliferated proliferative providing responsive retrovirally stat5 tepc transduced varied
Tagcloud (Intersection) ?