MARK3 and FANCF

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		MARK3	FANCF
Gene Name		MAP/microtubule affinity-regulating kinase 3	Fanconi anemia, complementation group F
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Extracellular Vesicular Exosome	Nucleoplasm Fanconi Anaemia Nuclear Complex
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Molecular_function Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Protein Phosphorylation	Ovarian Follicle Development DNA Repair Spermatogenesis Biological_process Protein Ubiquitination
Pathways			Fanconi Anemia pathway
Drugs
Diseases
GWAS		Bone mineral density ( 22504420)
Protein-Protein Interactions		27 interactors: ANKRD7 ASB13 ATP6V0C CDC25C CHGB CPSF4 DYNLL1 FANCF HDAC7 KSR1 MAP2 MAPT MITF NOL11 PIM1 PKP2 PMPCB PNPLA2 PRKCQ SAAL1 SFN TCEA2 TTR VPS11 YWHAG YWHAQ YWHAZ	7 interactors: FANCA FANCC FANCE FANCG HES1 MARK3 OLFM2
Entrez ID		4140	2188
HPRD ID		04058	04589
Ensembl ID		ENSG00000075413	ENSG00000183161
Uniprot IDs		P27448 Q86U11	A3KME0 Q9NPI8
PDB IDs		2QNJ 3FE3	2IQC
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrion Organization Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Organelle Organization Apoptotic Process Positive Regulation Of Intracellular Transport Regulation Of Intracellular Transport Programmed Cell Death Cell Death Death Organelle Organization Apoptotic Signaling Pathway Regulation Of Organelle Organization Regulation Of Apoptotic Process Positive Regulation Of Transport Regulation Of Cellular Component Organization Regulation Of Cell Death Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Signal Transduction G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Apoptotic Process Multicellular Organismal Development Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death System Development Intracellular Signal Transduction Regulation Of Cellular Localization Regulation Of Establishment Of Protein Localization Substantia Nigra Development Protein Targeting Regulation Of Protein Localization Developmental Process Cellular Response To Insulin Stimulus Neural Nucleus Development Signaling Anatomical Structure Development Regulation Of Phosphorylation Protein Targeting To Mitochondrion Regulation Of Cellular Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Intracellular Protein Transport Cell Communication Negative Regulation Of Apoptotic Process Positive Regulation Of T-helper 2 Cell Activation	DNA Repair Developmental Process Involved In Reproduction Cellular Response To DNA Damage Stimulus DNA Metabolic Process Single Organism Reproductive Process Reproductive Process Reproductive Structure Development Negative Regulation Of Stomach Neuroendocrine Cell Differentiation Negative Regulation Of Pancreatic A Cell Differentiation Pharyngeal Arch Artery Morphogenesis Lateral Inhibition Reproductive System Development Female Gonad Development Development Of Primary Female Sexual Characteristics Cellular Response To Stress Negative Regulation Of Forebrain Neuron Differentiation Negative Regulation Of Auditory Receptor Cell Differentiation Inhibition Of Neuroepithelial Cell Differentiation Negative Regulation Of Pro-B Cell Differentiation Negative Regulation Of Inner Ear Receptor Cell Differentiation Auditory Receptor Cell Fate Determination Trochlear Nerve Development Ascending Aorta Morphogenesis Positive Regulation Of Mitotic Cell Cycle, Embryonic Oculomotor Nerve Development Regulation Of Pro-B Cell Differentiation Regulation Of Auditory Receptor Cell Differentiation STAT Protein Import Into Nucleus Gonad Development Regulation Of Forebrain Neuron Differentiation Cardiac Neural Crest Cell Development Involved In Outflow Tract Morphogenesis Regulation Of Mitotic Cell Cycle, Embryonic Regulation Of Timing Of Neuron Differentiation Forebrain Radial Glial Cell Differentiation Comma-shaped Body Morphogenesis Development Of Primary Sexual Characteristics Common Bile Duct Development Metanephric Nephron Tubule Morphogenesis Midbrain-hindbrain Boundary Morphogenesis Renal Interstitial Fibroblast Development Germ Cell Development S-shaped Body Morphogenesis Protein Complex Assembly Reproduction Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Neuron Fate Determination Auditory Receptor Cell Fate Commitment Negative Regulation Of Epidermal Cell Differentiation Positive Regulation Of Astrocyte Differentiation Radial Glial Cell Differentiation
Tagcloud ?		acrylamide amiloride bbmv benzoyl border brush cariporide dihydro guanidine guanidino hnhe1 ic50 isopro isopropyl lap1 methane methylsulphonyl micromol nhe nhe1 nhe2 nhe3 ok opossum propenyl pylidene rbnhe2 s3226 sulphonate	bloom brca1 centrosome circumference connected coregulated coregulation divergent e2f e2f3 exploiting fanca fanconi fluctuations govern id jointly mesh microcephaly networks predisposition rb1 retinoblastoma silico subcellular subnetwork upregulation vital
Tagcloud (Difference) ?		acrylamide amiloride bbmv benzoyl border brush cariporide dihydro guanidine guanidino hnhe1 ic50 isopro isopropyl lap1 methane methylsulphonyl micromol nhe nhe1 nhe2 nhe3 ok opossum propenyl pylidene rbnhe2 s3226 sulphonate	bloom brca1 centrosome circumference connected coregulated coregulation divergent e2f e2f3 exploiting fanca fanconi fluctuations govern id jointly mesh microcephaly networks predisposition rb1 retinoblastoma silico subcellular subnetwork upregulation vital
Tagcloud (Intersection) ?