ARNT and MTA3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ARNT	MTA3
Gene Name		aryl hydrocarbon receptor nuclear translocator	metastasis associated 1 family, member 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm RNA Polymerase II Transcription Factor Complex	Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Aryl Hydrocarbon Receptor Activity Protein Binding Transcription Factor Binding Aryl Hydrocarbon Receptor Binding Enhancer Binding Sequence-specific DNA Binding Protein Heterodimerization Activity	Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding
	Biological Process	Response To Hypoxia Embryonic Placenta Development Positive Regulation Of Endothelial Cell Proliferation Transcription, DNA-templated Positive Regulation Vascular Endothelial Growth Factor Production Cell Differentiation Intracellular Receptor Signaling Pathway Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Sumoylation MRNA Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Glycolytic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Hormone Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Response To Hypoxia	Chromatin Organization Regulation Of Transcription, DNA-templated
Pathways		Cellular response to hypoxia Regulation of Hypoxia-inducible Factor (HIF) by oxygen Regulation of gene expression by Hypoxia-inducible Factor	Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Clearance
Drugs
Diseases
GWAS		Melanoma ( 21983785) Rhegmatogenous retinal detachment ( 23585552) Urate levels ( 23263486)
Protein-Protein Interactions		37 interactors: ADH5 AHR AHRR AIP ARNT2 BRCA1 CSNK2A1 DIABLO EP300 EPAS1 ESR1 GMNN GTF2F1 GTF2F2 HEY1 HEY2 HIF1A IRAK4 LSM8 MTA3 NCOA1 NCOA2 NCOA7 NCOR2 NPAS4 PML PTGES3 SENP6 SIM1 SIM2 SMAD9 SP1 SRC STRBP TNFAIP1 TRIP11 UBE2I	6 interactors: ARNT BCL6 ESR1 GRB2 KDM1A NACC2
Entrez ID		405	57504
HPRD ID		00524	12359
Ensembl ID		ENSG00000143437	ENSG00000057935
Uniprot IDs		A8K6P0 B0AZM1 F8WAP6 P27540	E7EQY4 Q9BTC8
PDB IDs		1D7G 1X0O 2A24 2ARN 2B02 2HV1 2K7S 3F1N 3F1O 3F1P 3H7W 3H82 4EQ1 4GHI 4GS9 4H6J
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Gene Expression Regulation Of Transcription, DNA-templated RNA Metabolic Process Positive Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Rhythmic Process Signal Transduction Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Cellular Metabolic Process Tube Development Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Developmental Process Involved In Reproduction Signaling Intracellular Receptor Signaling Pathway Embryonic Placenta Development Cell Communication Reproductive Structure Development Response To Stimulus Negative Regulation Of Biosynthetic Process Reproductive System Development Regulation Of Cellular Process Embryo Development Organ Development Single Organism Reproductive Process Multicellular Organismal Development	Positive Regulation Of Cell Proliferation Regulation Of Signal Transduction Positive Regulation Of Hormone Biosynthetic Process Regulation Of Signaling Regulation Of Cell Proliferation Positive Regulation Of Erythrocyte Differentiation Regulation Of Intracellular Signal Transduction Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Hormone Biosynthetic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Immune System Process Regulation Of Hormone Metabolic Process Regulation Of Erythrocyte Differentiation Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Signal Transduction Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Signaling Single Organism Reproductive Process Negative Regulation Of Intracellular Signal Transduction Positive Regulation Of Signal Transduction Regulation Of Immune System Process Reproductive Process Negative Regulation Of Gene Expression Positive Regulation Of Myeloid Cell Differentiation Reproductive Structure Development Organ Development Reproductive System Development In Utero Embryonic Development Regulation Of Apoptotic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Cell Death RNA Metabolic Process Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle By Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Primitive Erythrocyte Differentiation Chromatin Modification Cell Differentiation Positive Regulation Of Metabolic Process Gene Expression Embryonic Placenta Development Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Histone Modification Regulation Of Response To DNA Damage Stimulus Cellular Macromolecule Biosynthetic Process Cell Development Macromolecule Biosynthetic Process Chromatin Organization Developmental Process Involved In Reproduction Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Intrinsic Apoptotic Signaling Pathway
Tagcloud ?		belong bhlh cobalt confers dimerizes frame helix heterodimer heterodimeric heterologous hif1alpha hif2alpha hif3alpha hifs hrd1 hre hypoxia identity pas prototype reading recognizes resultant shares superfamily tacgtg tension thymus transfections	adds aggressive axis claudin clinicopathological cohorts depicted determining dfs diminished diminution discovered downregulated drives ductal emt lowest mesenchymal operable partly progesterone raf registered rkip shorter sized snail subtype subtyping
Tagcloud (Difference) ?		belong bhlh cobalt confers dimerizes frame helix heterodimer heterodimeric heterologous hif1alpha hif2alpha hif3alpha hifs hrd1 hre hypoxia identity pas prototype reading recognizes resultant shares superfamily tacgtg tension thymus transfections	adds aggressive axis claudin clinicopathological cohorts depicted determining dfs diminished diminution discovered downregulated drives ductal emt lowest mesenchymal operable partly progesterone raf registered rkip shorter sized snail subtype subtyping
Tagcloud (Intersection) ?